Recombinant HLA DQ anticorps (full length)

N° du produit ABIN6654368

Cet anticorps anti-HLA DQ Monoclonal Lapin (Clone HLA-DQA1-2866R) (ABIN6654368) détecte spécifiquement HLA DQ dans FACS et IF. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Recombinant HLA DQ anticorps (full length) (ABIN6654368)

Antigène: HLA DQ (HLA-DQ) (MHC Class II HLA-DQ (HLA-DQ))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp HLA DQ est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: HLA-DQA1-2866R

Détail du produit anti-HLA DQ anticorps

Épitope: full length

Fonction: Recombinant HLA-DQ Antibody (MHC II)

Purification: Protein A affinity chromatography

Immunogène: Full length recombinant human protein was used as the immunogen for the recombinant HLA-DQ antibody.

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal dilution of the recombinant HLA-DQ antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the recombinant HLA-DQ antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur HLA DQ

Antigène: HLA DQ (HLA-DQ) (MHC Class II HLA-DQ (HLA-DQ))

Autre désignation: HLA-DQ

Sujet: Recognizes a DQ antigen, which is a dimer of 60 kDa. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B Lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa. It is encoded by 5 exons, exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation.

UniProt: P01908