Recombinant HLA DQ anticorps (full length)

N° du produit ABIN6654369

Cet anticorps Lapin Monoclonal détecte spécifiquement HLA DQ dans FACS et IF. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Recombinant HLA DQ anticorps (full length) (ABIN6654369)

Antigène: HLA DQ (HLA-DQ) (MHC Class II HLA-DQ (HLA-DQ))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp HLA DQ est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Classe de qualité: Carrier-free

Clone: HLA-DQA1-2866R

Détail du produit anti-HLA DQ anticorps

Épitope: full length

Fonction: Recombinant HLA-DQ Antibody (MHC II) (azide and preservative free)

Purification: Protein A affinity chromatography

Immunogène: Full length recombinant human protein was used as the immunogen for the recombinant HLA-DQ antibody.

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal dilution of the recombinant HLA-DQ antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the recombinant HLA-DQ antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur HLA DQ

Antigène: HLA DQ (HLA-DQ) (MHC Class II HLA-DQ (HLA-DQ))

Autre désignation: HLA-DQ

Sujet: Recognizes a DQ antigen, which is a dimer of 60 kDa. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B Lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa. It is encoded by 5 exons, exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation.

UniProt: P01908