Recombinant NEFH anticorps

N° du produit ABIN6654556

L’anticorps anti-NEFH Monoclonal Lapin est utilisé pour la détection de NEFH dans des échantillons de Humain. Il a été validé pour WB, FACS et IHC (p).

Aperçu rapide pour Recombinant NEFH anticorps (ABIN6654556)

Antigène: NEFH (Neurofilament, Heavy Polypeptide (NEFH))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp NEFH est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: NEFL-H-2324R

Détail du produit anti-NEFH anticorps

Fonction: Recombinant Neurofilament Antibody / Heavy (azide and preservative free)

Purification: Protein A affinity

Immunogène: Recombinant human protein (heavy subunit) was used as the immunogen for the recombinant Neurofilament antibody.

Isotype: IgG, kappa

Information d'application

Indications d'application: The usable concentrations in the Applications Details are suggestions only. The use of different protocols/secondaries/substrates may require the recombinant Neurofilament antibody to be titered for optimal performance.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the recombinant Neurofilament antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur NEFH

Antigène: NEFH (Neurofilament, Heavy Polypeptide (NEFH))

Autre désignation: Neurofilament (-Heavy) / NF-H / NEFH

Sujet: This MAb reacts with a 200 kDa protein, identified as heavy sub-unit of neurofilaments (NF-H). Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68 kDa (NF-L), 160 kDa (NF-M) and 200 kDa (NF-H). Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express neurofilament.

UniProt: P12036