MTAP anticorps (AA 97-196)
Aperçu rapide pour MTAP anticorps (AA 97-196) (ABIN6654902)
Antigène
Voir toutes MTAP AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 97-196
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Purification
- Purified
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Pureté
- Protein A affinity chromatography
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Immunogène
- A portion of amino acids 97-196 from the human protein was used as the immunogen for the recombinant MTAP antibody.
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Isotype
- IgG kappa
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Indications d'application
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The stated application concentrations are suggested starting points. Titration of the recombinant MTAP antibody may be required due to differences in protocols and secondary/substrate sensitivity.
1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Western blot: 1-2 μg/mL,Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1) -
Restrictions
- For Research Use only
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Buffer
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store the recombinant MTAP antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
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- MTAP (Methylthioadenosine phosphorylase (MTAP))
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Autre désignation
- MTAP
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Sujet
- Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. [UniProt]
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Pathways
- Ribonucleoside Biosynthetic Process, Methionine Biosynthetic Process
Antigène
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