MTAP anticorps (AA 97-196)

N° du produit ABIN6654904

L’anticorps Lapin Monoclonal anti-MTAP a été validé pour WB et IHC (p). Il convient pour détecter MTAP dans des échantillons de Humain.

Aperçu rapide pour MTAP anticorps (AA 97-196) (ABIN6654904)

Antigène: MTAP (Methylthioadenosine phosphorylase (MTAP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp MTAP est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: SMTP-1R

Détail du produit anti-MTAP anticorps

Épitope: AA 97-196

Purification: Purified

Pureté: Protein A affinity chromatography

Immunogène: A portion of amino acids 97-196 from the human protein was used as the immunogen for the recombinant MTAP antibody.

Isotype: IgG kappa

Information d'application

Indications d'application: The stated application concentrations are suggested starting points. Titration of the recombinant MTAP antibody may be required due to differences in protocols and secondary/substrate sensitivity.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Western blot: 1-2 μg/mL,Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1)

Restrictions: For Research Use only

Stockage

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the recombinant MTAP antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Détails sur MTAP

Antigène: MTAP (Methylthioadenosine phosphorylase (MTAP))

Autre désignation: MTAP

Sujet: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. [UniProt]

Pathways: Ribonucleoside Biosynthetic Process, Methionine Biosynthetic Process