Rho-related GTP-binding protein anticorps

N° du produit ABIN6655039

N° du produit (Fournisseur): 200-301-e29

L’anticorps Souris Monoclonal anti-Rho-related GTP-binding protein a été validé pour WB et IHC. Il convient pour détecter Rho-related GTP-binding protein dans des échantillons de Boeuf (Vache).

Aperçu rapide pour Rho-related GTP-binding protein anticorps (ABIN6655039)

Antigène: Rho-related GTP-binding protein (RhO (pan))

Reactivité: Boeuf (Vache)

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Rho-related GTP-binding protein est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: 1D4

Détail du produit anti-Rho-related GTP-binding protein anticorps

N° du produit (Fournisseur): 200-301-e29

Fournisseur: Rockland

Fonction: Rhodopsin Antibody

Réactivité croisée (Details): Anti-Rhodopsin antibody is directed against bovine Rhodopsin.

Purification: Rhodopsin antibodies are Protein G purified from cell culture supernantant.

Immunogène: Anti-Rhodopsin Monoclonal Antibody was produced in mouse by repeated immunizations with purified native bovine rhodopsin.

Isotype: IgG1

Information d'application

Indications d'application:

Immunohistochemistry_Dilution: 1:100

Western_Blot_Dilution: 1:1000

Commentaires:

Anti-Rhodopsin antibody has been tested in Western Blot and Immunohistochemistry. Expect a band of approximately 39 kDa in size corresponding to the rhodopsin proteins in Western blot in the appropriate cell lysate or extract. Researchers should determine optimal titers for applications that are not stated below.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Date de péremption: 12 months

Détails sur Rho-related GTP-binding protein

Antigène: Rho-related GTP-binding protein (RhO (pan))

Autre désignation: RHO

Sujet:

Synonyms: OPN2, Rhodopsin, RHO, Anti-Rhodopsin monoclonal, photoreceptor proteins

Background: Rhodopsin antibody detects rhodopsin which is a photoreceptor protein found in retinal rods. It is a complex formed by the binding of retinaldehyde, the oxidized form of retinol, to the protein opsin and undergoes a series of complex reactions in response to visible light resulting in the transmission of nerve impulses to the brain. Mutation of the rhodopsin gene is a major contributor to various retinopathies such as retinitis pigmentosa. The disease-causing protein generally aggregates with ubiquitin in inclusion bodies, disrupts the intermediate filament network and impairs the ability of the cell to degrade non-functioning proteins which leads to photoreceptor apoptosis. Other mutations on rhodopsin lead to X-linked congenital stationary night blindness, mainly due to constitutive activation, when the mutations occur around the chromophore binding pocket of rhodopsin. Several other pathological states relating to rhodopsin have been discovered including poor post-Golgi trafficking, dysregulative activation, rod outer segment instability and arrestin binding. Anti-Rhodopsin Antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.

Gene Name: RHO

ID gène: 509933

UniProt: P02699