Calretinin anticorps

N° du produit ABIN6655054

Détail du produit anti-Calretinin anticorps

Antigène: Calretinin (CALB2) (Calbindin 2 (CALB2))

Reactivité: Cobaye

Hôte: Mouton

Clonalité: Polyclonal

Conjugué: Cet anticorp Calretinin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Fluorescence Microscopy (FM)

Réactivité croisée: Cobaye, Rat (Rattus)

Réactivité croisée (Details): Cross reactivity with Calretinin from other species has not been determined

Purification: Anti-Calretinin Antibody is directed against guinea pig Calretinin protein. The antibody was purified from monospecific antiserum by Protein A chromatography. Anti-Calretinin antibody reacts with Calretinin from rat and guinea pig sources. . However, reactivity is also expected from the following species based on 100% sequence homology: human, mouse, non-human primates.

Immunogène:

Immunogen: Anti-Calretinin Antibody was produced by repeated immunizations with native guinea pig calretinin.

Immunogen Type: Native Protein

Isotype: IgG

Information d'application

Indications d'application:

Immunohistochemistry Dilution: 1:500

Application Note: Anti-Calretinin antibody is suitable for use in ELISA, Western Blotting, IHC and IF. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 29 kDa in size corresponding to the calretinin protein in Western blots using rat brain lysate. Use this calretinin antibody for Immunohistochemistry on formalin or paraformaldehyde perfused rat brain tissue sections.

ELISA Dilution: 1:10,000

Western Blot Dilution: 1:1000

IF Microscopy Dilution: 1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 0.01 M Tris Cl, 0.15 M Sodium Chloride, 0.001 M EDTA, pH 7.4

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Références pour anticorps anti-Calretinin (ABIN6655054)

Molgaard, Ulrichsen, Boggild, Holm, Vaegter, Nyengaard, Glerup: "Immunofluorescent visualization of mouse interneuron subtypes." dans: F1000Research, Vol. 3, pp. 242, (2014) (PubMed).

Détails sur Calretinin

Antigène: Calretinin (CALB2) (Calbindin 2 (CALB2))

Autre désignation: Calretinin (CALB2 Produits)

Synonymes: anticorps CAB29, anticorps CAL2, anticorps CR, anticorps calb2l, anticorps wu:fq18e08, anticorps zgc:73115, anticorps calb2, anticorps wu:fq17g09, anticorps zgc:73099, anticorps calbindin 2, anticorps calbindin 2a, anticorps calbindin 2b, anticorps CALB2, anticorps Calb2, anticorps calb2a, anticorps calb2b

Sujet:

Synonyms: CR, Calb2, CAB29

Background: Calretinin antibody reacts with calretinin which is a calcium-binding protein involved in calcium signaling. Calretinin is abundantly expressed throughout the central nervous system, retina and many other tissues. Studies have shown that calretinin may play a role in neuroprotection by buffering intracellular calcium. Additionally, calretinin selectively stains mesothelial cells thus making it an important marker for differentiating malignant mesothelioma from carcinomas. Anti-Calretinin antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.

Gene Name: CALB2

ID gène: 117059

NCBI Accession: NP_446440

UniProt: P47728