MBD1 anticorps (N-Term)

N° du produit ABIN6655183

N° du produit (Fournisseur): 600-401-x42

L’anticorps Lapin Polyclonal anti-MBD1 a été validé pour WB, ELISA et ChIP. Il convient pour détecter MBD1 dans des échantillons de Humain.

Aperçu rapide pour MBD1 anticorps (N-Term) (ABIN6655183)

Antigène: MBD1 (Methyl-CpG Binding Domain Protein 1 (MBD1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MBD1 est non-conjugé

Application: Western Blotting (WB), ELISA, Chromatin Immunoprecipitation (ChIP)

Détail du produit anti-MBD1 anticorps

Épitope: N-Term

N° du produit (Fournisseur): 600-401-x42

Fournisseur: Rockland

Fonction: MBD1 Antibody

Réactivité croisée (Details): Cross reactivity with other species was not tested.

Purification: Anti-MBD1 Antibody was purified by affinity purification.

Stérilité: Sterile filtered

Immunogène: Anti-MBD1 Antibody was produced in rabbits by repeated immunizations with a synthetic peptide containing a sequence from the N-terminus of human MBD1.

Isotype: IgG

Information d'application

Indications d'application:

ChIP_Dilution: 1.5 μg per IP

ELISA_Dilution: 1:1,000

Western_Blot_Dilution: 1:500

Commentaires:

Anti-MBD1 Antibody is tested for Chromatin Immunoprecipitation, ELISA and Western Blots. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 75 kDa in the appropriate cell lysate or extract.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2

Stabilizer: None

Preservative: 0.05 % (w/v) Sodium Azide and 0.05 % ProClin 300

Agent conservateur: ProClin, Sodium azide

Précaution d'utilisation: This product contains Sodium azide and ProClin: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Date de péremption: 12 months

Détails sur MBD1

Antigène: MBD1 (Methyl-CpG Binding Domain Protein 1 (MBD1))

Autre désignation: MBD1

Sujet:

Synonyms: Methyl-CpG-binding domain protein 1, CXXC-type zinc finger protein 3, Methyl-CpG-binding protein MBD1, Protein containing methyl-CpG-binding domain 1, CXXC3, PCM1

Background: MBD1 is a transcriptional repressor that specifically binds to methylated CpG dinucleotides in promoter sequences. MBD1 acts by recruiting a variety of histone deacetylases (HDAC's) and chromatin remodelling factors. MBD1-dependent transcriptional repression is mediated by ATF7IP through the recruitment of factors such as the histone methyltransferase SETDB1. MBD1 probably forms a complex with SETDB1 and ATF7IP which couples DNA methylation to H3K9 trimethylation and represses transcription. Anti-MBD1 Antibody is ideal for research in Epigenetics, Gene Expression and Chromatin Remodeling.

Gene Name: MBD1

ID gène: 4152

NCBI Accession: NP_001191065

UniProt: Q9UIS9