MECP2 anticorps (C-Term)

N° du produit ABIN6655271

N° du produit (Fournisseur): 600-401-x39

Cet anticorps anti-MECP2 est un anticorps Lapin Polyclonal détectant MECP2 dans WB, ELISA et ChIP. Adapté pour Humain.

Aperçu rapide pour MECP2 anticorps (C-Term) (ABIN6655271)

Antigène: MECP2 (Methyl CpG Binding Protein 2 (MECP2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MECP2 est non-conjugé

Application: Western Blotting (WB), ELISA, Chromatin Immunoprecipitation (ChIP)

Détail du produit anti-MECP2 anticorps

Épitope: C-Term

N° du produit (Fournisseur): 600-401-x39

Fournisseur: Rockland

Fonction: MeCP2 Antibody

Réactivité croisée (Details): This product reacts with human MeCP2.

Purification: Anti-MeCP2 Antibody was purified by affinity purification.

Stérilité: Sterile filtered

Immunogène: Anti-MeCP2 Antibody was produced in rabbits by repeated immunizations with a synthetic peptide containing the C-terminal region of human MeCP2.

Isotype: IgG

Information d'application

Indications d'application:

ChIP_Dilution: 5 μg per IP

ELISA_Dilution: 1:1,000

Western_Blot_Dilution: 1:1,000

Commentaires:

Anti-MeCP2 Antibody is tested for Chromatin Immunoprecipitation, ELISA and Western Blots. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 70 kDa in the appropriate cell lysate or extract.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2

Stabilizer: None

Preservative: 0.05 % (w/v) Sodium Azide and 0.05 % ProClin 300

Agent conservateur: ProClin, Sodium azide

Précaution d'utilisation: This product contains Sodium azide and ProClin: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Date de péremption: 12 months

Détails sur MECP2

Antigène: MECP2 (Methyl CpG Binding Protein 2 (MECP2))

Autre désignation: MeCP2

Sujet:

Synonyms: Methyl-CpG-binding protein 2, MeCP-2 protein, AUTSX3, MRX16, MRX79, MRXS13, MRXSL, PPMX, RTS, RTT

Background: MeCP2 is a chromosomal protein with abundant binding sites in the chromatin. It belongs to the family of methyl CpG binding proteins which also comprises MBD1, MBD2, MBD3 and MBD4. MeCP2 can bind specifically to methylated promoters, thereby repressing transcription. This transcriptional repression is mediated through interaction with histone deacetylase and the corepressor SIN3A. MeCP2 also is essential for development. Mutations in MeCP2 are the cause of several types of mental retardation including Rett syndrome, a progressive neurological disorder that causes mental retardation in females and mental retardation syndromic X-linked type 13, and may also be involved in Angelman syndrome and susceptibility to some types of autism. Anti-MeCP2 Antibody is ideal for research in Epigenetics, Embryonic Development and Neuroscience.

Gene Name: MECP2

ID gène: 4204

NCBI Accession: NP_001104262

UniProt: P51608

Pathways: Inositol Metabolic Process, Chromatin Binding, Synaptic Membrane