CXCR2 anticorps (Internal Region)

N° du produit ABIN6655456

N° du produit (Fournisseur): 600-401-p54

L’anticorps Lapin Polyclonal anti-CXCR2 a été validé pour WB. Il convient pour détecter CXCR2 dans des échantillons de Humain.

Aperçu rapide pour CXCR2 anticorps (Internal Region) (ABIN6655456)

Antigène: CXCR2 (Chemokine (C-X-C Motif) Receptor 2 (CXCR2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CXCR2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CXCR2 anticorps

Épitope: Internal Region

N° du produit (Fournisseur): 600-401-p54

Fournisseur: Rockland

Fonction: CXCR2 Antibody

Réactivité croisée (Details): Anti-CXCR2 antibody is directed against human CXCR2 protein.

Purification: The product was affinity purified from monospecific antiserum by immunoaffinity purification.

Immunogène: CXCR2 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region of human CXCR2.

Isotype: IgG

Information d'application

Indications d'application: Optional[Neutralization_Dilution]: 0.5 μg/mL

Commentaires:

Anti-CXCR2 is tested for Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~40.8 kDa corresponding to the appropriate cell lysate or extract.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution:

Reconstitution_Buffer: Restore with deionized water (or equivalent)

Reconstitution_Volume: 100 μL

Buffer:

Buffer: 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide

Stabilizer: 5 mg BSA

Preservative: 0.05 mg Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at 4° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Date de péremption: 12 months

Détails sur CXCR2

Antigène: CXCR2 (Chemokine (C-X-C Motif) Receptor 2 (CXCR2))

Autre désignation: CXCR2

Sujet:

Synonyms: CDw128b,GRO/MGSA receptor,High affinity interleukin-8 receptor B,

Background: CXCR2 is a receptor for Interleukin 8, which is a powerful neutrophil chemotactic factor. It is a member of the GPCR family (subfamily, chemokine). Binding of IL8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL8 with a high affinity and to GRO/MGSA and NAP2 also with a high affinity. It has been reported to be expressed in a wide variety of tissues. ESTs have been isolated from human placenta and thymus libraries. This antibody is suitable for researchers interested in cell signaling research.

Gene Name: CXCR2

ID gène: 3579

NCBI Accession: NP_001161770

UniProt: P25025

Pathways: cAMP Metabolic Process