Aquaporin 4 anticorps (C-Term)

N° du produit ABIN6656113

N° du produit (Fournisseur): 600-401-e92

L’anticorps Lapin Polyclonal anti-Aquaporin 4 a été validé pour WB, IHC, IF et FM. Il convient pour détecter Aquaporin 4 dans des échantillons de Rat.

Aperçu rapide pour Aquaporin 4 anticorps (C-Term) (ABIN6656113)

Antigène: Aquaporin 4 (AQP4)

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Aquaporin 4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Fluorescence Microscopy (FM)

Détail du produit anti-Aquaporin 4 anticorps

Épitope: C-Term

N° du produit (Fournisseur): 600-401-e92

Fournisseur: Rockland

Fonction: Aquaporin 4 Antibody

Réactivité croisée (Details): A BLAST analysis was used to suggest cross-reactivity with Aquaporin 4 from Human, Mouse, and Rat based on 100 % homology with the immunizing sequence.

Purification: Anti-Aquaporin 4 Antibody was purified by affinity chromatography.

Stérilité: Sterile filtered

Immunogène: Aquaporin 4 Antibody was produced from whole rabbit serum prepared by repeated immunizations with a synthetic peptide corresponding to the C-terminal region of rat aquaporin 4.

Isotype: IgG

Information d'application

Indications d'application:

IF_Microscopy_Dilution: 1:400

Western_Blot_Dilution: 1:1000-4000

Commentaires:

Anti-Aquaporin 4 Antibody is tested for use in WB, IHC, and IF microscopy. Expect a band approximately ~35kDa on specific lysates. May detect larger glycosylated bands ~50kDa. Specific conditions for reactivity should be optimized by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 50 % (v/v) Glycerol

Preservative: 0.1 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Date de péremption: 12 months

Détails sur Aquaporin 4

Antigène: Aquaporin 4 (AQP4)

Autre désignation: Aquaporin 4

Sujet:

Synonyms: AQP4, Aquaporin-4, Mercurial-insensitive water channel, MIWC, WCH4

Background: Aquaporins selectively conduct water molecules in and out of the cell, while preventing the passage of ions and other solutes. Known as water channels, they are integral membrane pore proteins. Aquaporin 4 is constitutively expressed in the basolateral cell membrane of princinpal collecting duct cells in the kidney and provide a pathway for water to exit these cells. It is also expressed in astrocytes and is upregulated by direct insult to the CNS. Aquaporin 4 has been propsed as the primary autoimmune target in neuromyelitis optica.

Gene Name: Aqp4

ID gène: 25293

NCBI Accession: NP_036957

UniProt: P47863

Pathways: Sensory Perception of Sound