SMAD7 anticorps

N° du produit ABIN6656373

N° du produit (Fournisseur): 200-401-i16

Cet anticorps Lapin Polyclonal détecte spécifiquement SMAD7 dans WB, ELISA et IHC. Il présente une réactivité envers Humain.

Aperçu rapide pour SMAD7 anticorps (ABIN6656373)

Antigène: SMAD7 (SMAD, Mothers Against DPP Homolog 7 (SMAD7))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SMAD7 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-SMAD7 anticorps

N° du produit (Fournisseur): 200-401-i16

Fournisseur: Rockland

Fonction: SMAD7 Antibody

Réactivité croisée (Details): A BLAST analysis was used to suggest cross-reactivity with Anti-SMAD7 from human, rat, sheep and mouse based on 100 % homology with the immunizing sequence.

Purification: Anti-SMAD7 Antibody was purified by Protein G chromatography.

Immunogène: SMAD7 Antibody was produced from whole rabbit serum prepared by repeated immunizations with SMAD7 peptide.

Isotype: IgG

Information d'application

Indications d'application: Optional[Neutralization_Dilution]: 2-5 μg/mL

Commentaires:

Anti-SMAD7 antibody is tested for use in WB, ELISA, and IHC. Expect a band approximately 46kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 0.05 % BSA

Preservative: 0.05 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Date de péremption: 12 months

Détails sur SMAD7

Antigène: SMAD7 (SMAD, Mothers Against DPP Homolog 7 (SMAD7))

Autre désignation: SMAD7

Sujet:

Synonyms: MADH7, MADH8

Background: Anti-SMAD7 MADH7 antibody detects human SMAD7 MADH7. SMADs are members of the MAD-related family of molecules. MAD-related proteins are a family of intracellular proteins that are essential components in the signaling pathways of the serine/threonine kinase receptors of the transforming growth factor beta superfamily. SMADs can be divided into receptor-regulated SMADs (R-SMADs: SMAD1, 2, 5, 8 and 9), common-mediator SMAD (co-SMAD: SMAD4), and inhibitory SMADs (I-SMADs: SMAD6 and SMAD7). SMAD1, SMAD5, SMAD8 and SMAD9 have high degrees of homology and antibodies are available that recognize sequences common to all of them. SMAD8 and SMAD9 are typically used as alternate names for one another in the literature. Anti-SMAD7 MADH7 antibody is ideal for investigators involved kinase and phosphatase research.

Gene Name: SMAD7

ID gène: 4092

NCBI Accession: NP_001177750

UniProt: O15105

Pathways: Interferon-gamma Pathway, Cell-Cell Junction Organization