PCLO anticorps

N° du produit ABIN6657340

N° du produit (Fournisseur): 600-401-g30

L’anticorps Lapin Polyclonal anti-PCLO a été validé pour WB, IHC et FM. Il convient pour détecter PCLO dans des échantillons de Humain.

Aperçu rapide pour PCLO anticorps (ABIN6657340)

Antigène: PCLO (Piccolo (Presynaptic Cytomatrix Protein) (PCLO))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PCLO est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Fluorescence Microscopy (FM)

Détail du produit anti-PCLO anticorps

N° du produit (Fournisseur): 600-401-g30

Fournisseur: Rockland

Fonction: Piccolo Antibody

Réactivité croisée (Details): A BLAST analysis was used to suggest cross-reactivity with Piccolo from Human, Mouse, and Rat based on 100 % homology with the immunizing sequence.

Purification: Anti-Piccolo Antibody was purified by affinity chromatography.

Stérilité: Sterile filtered

Immunogène: Piccolo Antibody was produced from whole rabbit serum prepared by repeated immunizations raised against full length protein.

Isotype: IgG

Information d'application

Indications d'application:

IF_Microscopy_Dilution: 1 μg/mL

Western_Blot_Dilution: 1:1000

Commentaires:

Anti-Piccolo Antibody is tested for use in WB and IHC. Expect a band approximately ~550kDa corresponding to the molecular weight of Piccolo. Multiple isoforms can be detected. Specific conditions for reactivity should be optimized by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 50 % (v/v) Glycerol

Preservative: 0.1 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Date de péremption: 12 months

Détails sur PCLO

Antigène: PCLO (Piccolo (Presynaptic Cytomatrix Protein) (PCLO))

Autre désignation: PCLO

Sujet:

Synonyms: Protein piccolo, Aczonin, PCLO, ACZ, KIAA0559

Background: Piccolo, also referred to as Aczonin, is a large protein which consists of an N-terminal Zn2+ finger, several piccolo-bassoon homology domains and C-terminal PDZ and C2 domains. In general it is found together with bassoon, a related huge multi-domain protein of the CAZ (cytoskeletal matric assembled at active zones). Piccolo is a scaffolding protein for proteins involved in endo- and exocytosis of synaptic vesicles. Piccolo has also been shown to interfere with clathrin medicated endocytosis by binding to the F-actin and dynamin binding protein Abp1.

Gene Name: PCLO

ID gène: 27445

NCBI Accession: NP_055325

UniProt: Q9Y6V0

Pathways: Hormone Transport, Synaptic Vesicle Exocytosis