THRA anticorps (N-Term)

N° du produit ABIN6657352

N° du produit (Fournisseur): 209-301-e67

L’anticorps Souris Monoclonal anti-THRA a été validé pour WB. Il convient pour détecter THRA dans des échantillons de Humain.

Aperçu rapide pour THRA anticorps (N-Term) (ABIN6657352)

Antigène: THRA (Thyroid Hormone Receptor, alpha (THRA))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp THRA est non-conjugé

Application: Western Blotting (WB)

Clone: 2103

Détail du produit anti-THRA anticorps

Épitope: N-Term

N° du produit (Fournisseur): 209-301-e67

Fournisseur: Rockland

Fonction: Thyroid Hormone Receptor alpha 1/2 Antibody

Réactivité croisée (Details): Anti-Thyroid Hormone Receptor alpha 1/2 antibody is directed against human Thyroid Hormone Receptor alpha 1/2 protein and is specific for the TR-α1 and the TR-α2 proteins.

Purification: Anti-Thyroid Hormone Receptor alpha 1/2 Antibody was purified by Protein G chromatography from cell culture supernatant followed by extensive dialysis against the buffer stated above.

Immunogène: Anti-Thyroid Hormone Receptor alpha 1/2 Monoclonal Antibody was produced by repeated immunizations with synthetic peptide corresponding to amino acid residues from the N-terminal region of Thyroid Hormone Receptor alpha.

Isotype: IgG1

Information d'application

Indications d'application: Optional[Neutralization_Dilution]: 1:1,000

Commentaires:

Thyroid Hormone Receptor alpha 1/2 antibody has been tested for use in Western Blot. The expected bands in western blot are 50kDa for TR-α1 and 58 kDa for the TR-α2 proteins. Researchers should determine optimal titers for applications that are not stated below.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Date de péremption: 12 months

Détails sur THRA

Antigène: THRA (Thyroid Hormone Receptor, alpha (THRA))

Autre désignation: THRA

Sujet:

Synonyms: mouse anti-Thyroid Hormone Receptor alpha 1/2 Antibody, mouse anti-Thra antibody, Nuclear receptor subfamily 1 group A member 1, V-erbA-related protein 7, EAR-7, c-erbA-1, c-erbA-alpha

Background: Thyroid Hormone Receptor alpha 1/2 antibody detects TRα1 and TRα2. Thyroid hormones are essential for development of the central nervous system and deficits in these hormones during development affects such cognitive functions as learning and memory. Thyroid hormones exert their physiological role mainly through binding to specific nuclear receptors including the predominant isoforms of thyroid hormone receptors TRα1, TRα2, TRβ1 and TRβ2. TRα1, TRβ1 and TRβ2 bind T3 with high affinity and also bind to thyroid hormone response elements (TREs) on chromatin to regulate the transcriptional processes in several target tissues, including adult rat brain. Anti-TRα1/ TRα2 Antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.

Gene Name: THRA

ID gène: 7067

UniProt: P10827

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Maintenance of Protein Location, Skeletal Muscle Fiber Development