PCLO anticorps

N° du produit ABIN6657442

N° du produit (Fournisseur): 200-301-g30

L’anticorps Souris Monoclonal anti-PCLO a été validé pour WB, FM, ELISA et IF. Il convient pour détecter PCLO dans des échantillons de Humain.

Aperçu rapide pour PCLO anticorps (ABIN6657442)

Antigène: PCLO (Piccolo (Presynaptic Cytomatrix Protein) (PCLO))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PCLO est non-conjugé

Application: Western Blotting (WB), Fluorescence Microscopy (FM), ELISA, Immunofluorescence (IF)

Clone: 6H9-B6

Détail du produit anti-PCLO anticorps

N° du produit (Fournisseur): 200-301-g30

Fournisseur: Rockland

Fonction: Piccolo Antibody

Réactivité croisée (Details): A BLAST analysis was used to suggest cross-reactivity with Piccolo from human, mouse, rat based on 100 % homology with the immunizing sequence.

Purification: Anti-Piccolo Antibody was purified by Protein G chromatography.

Stérilité: Sterile filtered

Immunogène: Piccolo Antibody was produced in mice by repeated immunizations raised against a full length protein.

Isotype: IgG2b kappa

Information d'application

Indications d'application:

ELISA_Dilution: 1:200

IF_Microscopy_Dilution: 1:100

Western_Blot_Dilution: 1:1000

Commentaires:

Anti-Piccolo Antibody is tested for use in WB, ICC/IF, and ELISA. Expect a band ~550kDa in specific lysate or tissue samples. Specific conditions for reactivity should be optimized by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 50 % (v/v) Glycerol

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Date de péremption: 12 months

Détails sur PCLO

Antigène: PCLO (Piccolo (Presynaptic Cytomatrix Protein) (PCLO))

Autre désignation: PCLO

Sujet:

Synonyms: ACZ Antibody, Aczonin Antibody, PCLO Antibody, Pico Antibody, presynaptic cytomatrix protein Antibody, protein piccolo, Brain-derived HLMN protein, Multidomain presynaptic cytomatrix protein

Background: Piccolo, also referred to as Aczonin, is a large protein which consists of an N-terminal Zn2+ finger, several piccolo-bassoon homology domains and C-terminal PDZ and C2 domains. In general it is found together with bassoon, a related huge multi-domain protein of the CAZ (cytoskeletal matric assembled at active zones). Piccolo is a scaffolding protein for proteins involved in endo- and exocytosis of synaptic vesicles. Piccolo has also been shown to interfere with clathrin medicated endocytosis by binding to the F-actin and dynamin binding protein Abp1.

Gene Name: Pclo

ID gène: 27445

NCBI Accession: NP_055325

UniProt: Q9Y6V0

Pathways: Hormone Transport, Synaptic Vesicle Exocytosis