Apelin anticorps (C-Term)
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- Antigène Voir toutes Apelin (APLN) Anticorps
- Apelin (APLN)
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Épitope
- C-Term
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Reactivité
- Humain, Rat, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Apelin est non-conjugé
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Application
- Western Blotting (WB)
- Réactivité croisée
- Humain, Souris, Rat (Rattus)
- Purification
- Anti-Apelin antibody is directed against human Apelin protein. The product was affinity purified from monospecific antiserum by immunoaffinity purification. A BLAST analysis was used to suggest reactivity with this protein from human, mouse, and rat based on 100% homology for the immunogen sequence. Cross reactivity with Apelin from other sources has not been determined.
- Immunogène
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Immunogen: Apelin affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a sequence at the C-terminal of human Apelin.
Immunogen Type: Peptide
- Isotype
- IgG
- Top Product
- Discover our top product APLN Anticorps primaire
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- Indications d'application
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Application Note: Anti-Apelin is useful for Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~8.6 kDa corresponding to the appropriate cell lysate or extract.
Western Blot Dilution: 0.5 μg/mL
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
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Reconstitution Volume: 100 μL
Reconstitution Buffer: Restore with deionized water (or equivalent)
- Buffer
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Buffer: 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide
Stabilizer: 5 mg BSA
0.05 mg Thimerosal - Agent conservateur
- Thimerosal (Merthiolate)
- Précaution d'utilisation
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- RT,4 °C,-20 °C
- Stockage commentaire
- Store vial at 4° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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- Antigène
- Apelin (APLN)
- Autre désignation
- Apelin (APLN Produits)
- Synonymes
- anticorps APLN, anticorps Xapelin, anticorps xnpep2, anticorps preproapelin, anticorps 6030430G11Rik, anticorps Apel, anticorps APEL, anticorps XNPEP2, anticorps apelin, anticorps apelin S homeolog, anticorps apln, anticorps APLN, anticorps apln.S, anticorps Apln
- Sujet
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Synonyms: APJ endogenous ligand,
Background: Apelin is a neuropeptide expressed in the supraoptic and paraventricular nuclei that acts on specific receptors located on vasopressinergic neurons. The apelin gene to Xq25-q26.3 based on sequence similarity between the apelin sequence and a chromosome X PAC clone. This gene encodes a peptide that functions as an endogenous ligand for the G protein coupled receptor APJ. The encoded protein is synthesized as a prepropeptide that is processed into biologically active C-terminal fragments. The peptide fragments activate different tissue specific signaling pathways that regulate diverse biological functions including fluid homeostasis, cardiovascular function and insulin secretion. This protein also functions as a coreceptor for the human immunodeficiency virus 1. This antibody is suitable for researchers interested in neuroscience research.
Gene Name: APLN
- ID gène
- 8862
- NCBI Accession
- NP_059109
- UniProt
- Q9ULZ1
- Pathways
- Positive Regulation of Peptide Hormone Secretion, Hormone Activity, Feeding Behaviour
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