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Involucrin anticorps

Cet anticorps anti-Involucrin est un anticorps Souris Monoclonal détectant Involucrin dans WB, IHC et ELISA. Adapté pour Humain.
Rockland
N° du produit ABIN6657536
N° du produit (Fournisseur): 200-301-p39

Aperçu rapide pour Involucrin anticorps (ABIN6657536)

Antigène

Voir toutes Involucrin (IVL) Anticorps
Involucrin (IVL)

Reactivité

  • 116
  • 43
  • 43
  • 37
  • 27
  • 17
  • 11
  • 10
  • 5
  • 2
Humain

Hôte

  • 76
  • 48
Souris

Clonalité

  • 71
  • 53
Monoclonal

Conjugué

  • 50
  • 12
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp Involucrin est non-conjugé

Application

  • 50
  • 36
  • 33
  • 26
  • 23
  • 21
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  • 17
  • 15
  • 13
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  • 6
  • 4
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone

SY5
  • N° du produit (Fournisseur)

    200-301-p39

    Fournisseur

    Rockland

    Fonction

    Involucrin Antibody

    Réactivité croisée (Details)

    This product reacts with human and pig.

    Purification

    Anti-Involucrin antibody was purified from mouse ascites by protein A chromatography.

    Immunogène

    Involucrin antibody was produced in mice by repeated immunizations with human involucrin.

    Isotype

    IgG1
  • Indications d'application

    ELISA_Dilution: 1:20,000

    Immunohistochemistry_Dilution: 1:100-1:500

    Western_Blot_Dilution: 1 μg/mL

    Other: Immunocytochemistry: 1 μg/mL

    Commentaires

    Anti-Involucrin is tested for Immunohistochemistry -P, -F, Immunocytochemistry, and Western Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~68.5 kDa corresponding to the appropriate cell lysate or extract.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Reconstitution_Buffer: Neutral PBS

    Reconstitution_Volume: 1.0 mL

    Buffer

    Buffer: 1.2 % sodium acetate

    Stabilizer: 2 mg BSA

    Preservative: 0.01 % (w/v) Sodium Azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store vial at 4° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

    Date de péremption

    12 months
  • Antigène

    Involucrin (IVL)

    Autre désignation

    Involucrin

    Sujet

    Synonyms: INVO, IVL, Involucrin Antibody

    Background: Involucrin is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. The gene consists of 585 amino acids, 390 of which form a central decapeptide repeat, rich in glutamine and glutamic acid. The involucrin gene, encoding a protein of the terminally differentiated keratinocyte, is polymorphic in the human. Involucrin has previously been mapped to chromosome 1q21. The epidermal protein involucrin has been remodeled in the higher primates. And the existence of two populations of East Asian involucrin alleles gives support for the existence of a Eurasian stem lineage from which Caucasians and a part of the Asian population originated. This antibody is suitable for researchers interested in skin cell research.

    Gene Name: IVL

    ID gène

    3713

    NCBI Accession

    NP_005538

    UniProt

    P07476
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