Ataxin 1 anticorps (AA 164-197) (FITC)

N° du produit ABIN6657672

N° du produit (Fournisseur): 200-302-w69

Cet anticorps Souris Monoclonal détecte spécifiquement Ataxin 1 dans WB, IHC, ELISA et IP. Il présente une réactivité envers Souris.

Aperçu rapide pour Ataxin 1 anticorps (AA 164-197) (FITC) (ABIN6657672)

Antigène: Ataxin 1 (ATXN1)

Reactivité: Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Ataxin 1 est conjugé à/à la FITC

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)

Clone: S76-8

Détail du produit anti-Ataxin 1 anticorps (FITC)

Épitope: AA 164-197

N° du produit (Fournisseur): 200-302-w69

Fournisseur: Rockland

Fonction: Ataxin 1 Antibody Fluorescein

Réactivité croisée (Details): BLAST analysis suggests that it is 100 % identical to rat and 88 % identical to human.

Purification: Anti-Ataxin 1 Antibody was purified from concentrated tissue culture supernate by Protein G chromatography.

Stérilité: Sterile filtered

Immunogène: Anti-Ataxin 1 Antibody was produced by repeated immunization of mice with a synthetic peptide containing amino acids 164-197 of mouse Ataxin 1.

Isotype: IgG2b

Information d'application

Indications d'application:

Immunoprecipitation_Dilution: User Optimized

ELISA_Dilution: 1:10,000

Immunohistochemistry_Dilution: User Optimized

Western_Blot_Dilution: 1:1000

Other: ICC/IF: 1:100

Commentaires:

Anti-Ataxin 1 FITC Conjugated Antibody is tested for Western Blots, Immunohistochemistry and Immunoprecipitation. Expect a band approximately ~85 kDa on specific lysates or tissues. Specific conditions for reactivity should be optimized by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 50 % (v/v) Glycerol

Preservative: 0.1 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Date de péremption: 12 months

Détails sur Ataxin 1

Antigène: Ataxin 1 (ATXN1)

Autre désignation: Ataxin 1

Sujet:

Synonyms: Ataxin-1, ATX1, Atxn1, D6S504E, OTTHUMP00000016065, SCA1, Spinocerebellar ataxia type 1 protein

Background: Ataxin-1 is a member of the ATXN1 protein family and contains a single AXH domain. It is a neurodegenerative disorder protein thought to have a role in the metabolism of RNA as it has been shown to localize to the RNA and transcription dependent inclusions within the nucleus. A mutation of Ataxin-1 is the cause of spinocerebellar ataxia type-1 (SCA1), a progressive, neurodegenerative disease that is autosomal dominant and primarily affects the Purjinke cells found in brain stem neuronal populations and the cerebellum. Expression of Ataxin-1 is almost ubiquitous, except in the brain where it is isolated to populations of neurons.

Gene Name: Ataxin 1

ID gène: 20238

UniProt: P54254

Pathways: Synaptic Membrane