LGI1 anticorps (AA 37-113)

N° du produit ABIN6657718

N° du produit (Fournisseur): 200-301-w73

L’anticorps Souris Monoclonal anti-LGI1 a été validé pour WB, IHC et ELISA. Il convient pour détecter LGI1 dans des échantillons de Souris.

Aperçu rapide pour LGI1 anticorps (AA 37-113) (ABIN6657718)

Antigène: LGI1 (Leucine-Rich, Glioma Inactivated 1 (LGI1))

Reactivité: Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp LGI1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone: S283-7

Détail du produit anti-LGI1 anticorps

Épitope: AA 37-113

N° du produit (Fournisseur): 200-301-w73

Fournisseur: Rockland

Fonction: Lgi1 Antibody

Réactivité croisée (Details): BLAST analysis suggests that it is 100 % identical to rat, 98 % identical to human and ~50 % identical to LGI2, LGI3, and LGI4.

Purification: Anti-LGI1 Antibody was purified from concentrated tissue culture supernate by Protein G chromatography.

Stérilité: Sterile filtered

Immunogène: Anti-Lgi1 Antibody was produced by repeated immunization of mice with a fusion protein containing amino acids 37-113 (LRRNT domain and first LRR repeat) of mouse Lgi1.

Isotype: IgG2a

Information d'application

Indications d'application:

ELISA_Dilution: 1:10,000

Immunohistochemistry_Dilution: User Optimized

Western_Blot_Dilution: 1:1000

Commentaires:

Anti-LGI1 Antibody is suitable for Western Blots, Immunohistochemistry and Immunocytochemistry. Expect a band approximately ~60kDa on specific lysates or tissues. Specific conditions for reactivity should be optimized by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 50 % (v/v) Glycerol

Preservative: 0.1 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Date de péremption: 12 months

Détails sur LGI1

Antigène: LGI1 (Leucine-Rich, Glioma Inactivated 1 (LGI1))

Autre désignation: LGI1

Sujet:

Synonyms: ADLTE, ADPAEF, ADPEAF, Epitempin 1, EPT, ETL1, IB1099, leucine rich glioma inactivated 1, OTTHUMP00000020121, OTTHUMP00000020122

Background: The leucine-rich, glioma inactivated gene 1 (LGI1) was first identified as a candidate tumor suppressor gene for glioma and may play a role in other cancers. LGI1 is a member of a family of highly related proteins containing leucine-rich repeats (LRRs) which are highly similar to other transmembrane signaling molecules and receptors. LGI1 serves as a ligand to ADAM22, a metalloprotease localized at the synapse. Mutations in LGI1 account for nearly half of autodominant lateral temporal epilepsy (ADTLE), an epileptic syndrome characterized by focal seizures with predominant auditory symptoms. Two isoforms of LGI1 are known to exist, this LGI1 antibody will recognize only the longer form. Anti-LGI1 is ideal for research in Neuroscience and Cancer.

Gene Name: LGI1

ID gène: 56839

UniProt: Q9JIA1