SETD1A anticorps (Internal Region, N-Term)

N° du produit ABIN6657812

Détail du produit anti-SETD1A anticorps

Antigène: SETD1A (SET Domain Containing 1A (SETD1A))

Épitope: Internal Region, N-Term

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SETD1A est non-conjugé

Application: ELISA, Western Blotting (WB)

Réactivité croisée (Details): Cross reactivity with Setd1a from other species not tested.

Purification: Anti-Setd1a Antibody is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration.

Immunogène:

Immunogen: Anti-Setd1a Antibody was produced in rabbits by repeated immunizations with three different synthetic peptides of mouse Setd1a: two containing an amino acid sequence from the N-terminal region of the protein and one containing an amino acid sequence from the internal region of the protein.

Immunogen Type: Peptide

Information d'application

Indications d'application:

Application Note: Anti-Setd1a Antibody is suitable for ELISA and Western Blots. Specific conditions for reactivity should be optimized by the end user.  Expect a band approximately 186 kDa in the appropriate cell lysate or extract.

ELISA Dilution: 1:100

Western Blot Dilution: 1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

0.01 % (w/v) Sodium Azide

Stabilizer: None

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: RT,4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Détails sur SETD1A

Antigène: SETD1A (SET Domain Containing 1A (SETD1A))

Autre désignation: Setd1a (SETD1A Produits)

Synonymes: anticorps NV15594, anticorps KMT2F, anticorps Set1, anticorps Set1A, anticorps BC010250, anticorps Nsccn1, anticorps mKIAA0339, anticorps mNSC1, anticorps SET domain containing 1A, anticorps histone-lysine N-methyltransferase SETD1A, anticorps SETD1A, anticorps setd1a, anticorps Pat9b_4052, anticorps LOC100121025, anticorps Setd1a

Sujet:

Synonyms: Histone-lysine N-methyltransferase SETD1A, Lysine N-methyltransferase 2F, SET domain-containing protein 1A, hSET1A, Set1/Ash2 histone methyltransferase complex subunit SET1

Background: SETD1A is a component of the SET1 histone methyltransferase (HMT) complex. This complex specifically methylates lysine 4 of histone H3, but only if the neighboring lysine 9 residue is not yet methylated. Methylation of H3K4 represents a specific tag for epigenetic transcriptional activation. SETD1A shows a non-overlapping localization with SETD1B, suggesting that both proteins play a specific role in the epigenetic control of chromatin structure and gene expression. Anti-Setd1a Antibody is ideal for research in Epigenetics and Gene Expression.

Gene Name: SETD1A

ID gène: 9739

NCBI Accession: NP_055527

UniProt: O15047