TCRb anticorps (FITC)

N° du produit ABIN6657906

N° du produit (Fournisseur): 200-b02-n92

Cet anticorps Hamster Monoclonal détecte spécifiquement TCRb dans FACS, IP et FM. Il présente une réactivité envers Souris.

Aperçu rapide pour TCRb anticorps (FITC) (ABIN6657906)

Antigène: TCRb (T Cell Receptor beta Chain (TCRb))

Reactivité: Souris

Hôte: Hamster

Clonalité: Monoclonal

Conjugué: Cet anticorp TCRb est conjugé à/à la FITC

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Fluorescence Microscopy (FM)

Clone: H57-597

Détail du produit anti-TCRb anticorps (FITC)

N° du produit (Fournisseur): 200-b02-n92

Fournisseur: Rockland

Fonction: TCRbeta Fluorescein Antibody

Réactivité croisée (Details): Cross reactivity with TCRbeta from other sources has not been tested.

Purification: Fluorescein conjugated TCRbeta Monoclonal Antibody was purified from tissue culture supernatant via affinity chromatography and is directed against mouse TCRbeta.

Stérilité: Sterile filtered

Immunogène: Anti-TCRbeta Antibody (Monoclonal) was produced by repeated immunizations with TCRbeta antigen.

Isotype: IgG

Labeling Ratio: 2-8

Information d'application

Indications d'application:

Immunoprecipitation_Dilution: User Optimized

Flow_Cytometry_Dilution: 10 μL/10^6 cells (0.1 μg)

IF_Microscopy_Dilution: User Optimized

Other: Sufficient to run approximately 500 tests

Commentaires:

Anti-TCR beta is tested for FLOW and useful for Immunofluorescence and Immunoprecipitation using mouse spleen cells, or an appropriate cell type (where indicated). Researchers should determine optimal titers for applications that are not stated.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: 0.01 M Sodium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 0.1 % Gelatin

Preservative: 0.09 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store vial at 4° C prior to opening.  This product is stable for several weeks at 4° C as an undiluted liquid.  Dilute only prior to immediate use.  DO NOT FREEZE. This product is light sensitive.

Date de péremption: 6 months

Détails sur TCRb

Antigène: TCRb (T Cell Receptor beta Chain (TCRb))

Autre désignation: Tcrb

Sujet:

Synonyms: Tib, TCRbeta, T cell receptor beta chain, Tcrb

Background: The H57-597 antibody is specific for the beta chain of the mouse T cell Receptor (TCR). This cell surface protein combines with a second protein chain (alpha chain) to form the alpha-beta TCR that is expressed by NK1.1+ thymocytes, NKT cells, and the majority of peripheral T cells. A small number of T cells may express an alternative heteromer of gamma and delta protein chains, known as the gamma-delta TCR. These receptors participate in a complex with CD3, and with the co-receptors CD4 or CD8, to recognize and respond to antigens bound to MHC molecules on antigen-presenting cells. Such interactions promote T cell receptor signaling (T cell activation) and can result in a number of cellular responses including proliferation, differentiation, production of cytokines or activation-induced cell death.The H57-597 antibody is used as a phenotypic marker for T cells expressing the alpha-beta TCR. It is also widely used to cross-link surface TCR and thereby mimic TCR-mediated cell activation or induction of apoptosis. The antibody does not cross-react with cells expressing the gamma-delta TCR.

Gene Name: Tcrb

ID gène: 21577