TNNI3 anticorps (pSer43)

N° du produit ABIN6658030

N° du produit (Fournisseur): 600-401-x34

L’anticorps Lapin Polyclonal anti-TNNI3 a été validé pour WB et ELISA. Il convient pour détecter TNNI3 dans des échantillons de Souris.

Aperçu rapide pour TNNI3 anticorps (pSer43) (ABIN6658030)

Antigène: TNNI3 (Cardiac Troponin I (TNNI3))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TNNI3 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-TNNI3 anticorps

Épitope: pSer43

N° du produit (Fournisseur): 600-401-x34

Fournisseur: Rockland

Fonction: Troponin I (Cardiac) Phospho S43 Antibody

Réactivité croisée (Details): Anti-Phospho-Ser43 Troponin (cardiac) Antibody is directed against Troponin protein phosphorylated at S43.

Purification: The antibody was prepared from monospecific antiserum by immunoaffinity chromatography using phospho peptide coupled to agarose beads followed by solid phase adsorption(s) against non-phospho peptide and non-specific peptide to remove any unwanted reactivities.

Stérilité: Sterile filtered

Immunogène: Anti-Phospho-Ser43 Troponin (cardiac) Antibody was produced in rabbits by repeated immunizations with a synthetic phospho-peptide corresponding to amino acid residues surrounding Ser43 of mouse cardiac troponin I conjugated to KLH.

Isotype: IgG

Information d'application

Indications d'application:

ELISA_Dilution: 1:10,000

Western_Blot_Dilution: 1:1000

Commentaires:

Anti-Phospho-Ser43 Troponin (cardiac) Antibody has been tested by Western Blots and is specific for the ~25 kDa cardiac troponin I protein phosphorylated at Ser 43. Immunolabeling is greatly decreased with lambda-phosphatase treatment. Specific conditions for reactivity should be optimized by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Preservative: None

Agent conservateur: Without preservative

Stock: -20 °C

Stockage commentaire: Store vial at -20° C prior to opening in undiluted aliquots. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature.

Date de péremption: 12 months

Détails sur TNNI3

Antigène: TNNI3 (Cardiac Troponin I (TNNI3))

Autre désignation: Troponin I (Cardiac)

Sujet:

Synonyms: Troponin I cardiac muscle, Cardiac troponin I

Background: Troponin I (TnI) is 1 of 3 subunits, along with troponin C (TnC) and Troponin T (TnT) of troponin complex found in cardiac (cTnI) and fast skeletal (fsTnI) muscle. Protein kinase C-mediated phosphorylation of cardiac myofilament proteins has been shown to depress the actomyosin interaction and may be important during heart failure. Studies indicate that phosphorylation of Ser43 and Ser45 of cardiac troponin I plays a substantial role in the PKC-mediated depression. Troponin I pS43 Antibody is ideal for researchers interested in cancer research.

Gene Name: TNNI3

ID gène: 21954

NCBI Accession: NP_033432

UniProt: P48787