Peripherin anticorps

N° du produit ABIN6658100

N° du produit (Fournisseur): 900-301-e11

Cet anticorps anti-Peripherin est un anticorps Souris Monoclonal détectant Peripherin dans WB, IHC et FM. Adapté pour Rat.

Aperçu rapide pour Peripherin anticorps (ABIN6658100)

Antigène: Peripherin (PRPH)

Reactivité: Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Peripherin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Fluorescence Microscopy (FM)

Clone: 7C5

Détail du produit anti-Peripherin anticorps

N° du produit (Fournisseur): 900-301-e11

Fournisseur: Rockland

Fonction: Peripherin Antibody

Réactivité croisée (Details): Anti-Peripherin antibody is directed against rat Peripherin.

Purification: The antibody is protein G purified from concentrated clarified cell culture supernate.

Immunogène: Anti-Peripherin Antibody (Monoclonal) was produced by repeated immunizations with recombinant rat peripherin expressed in E. coli.

Isotype: IgG1

Information d'application

Indications d'application:

IF_Microscopy_Dilution: 1:200

Western_Blot_Dilution: 1:1000

Other: User Optimized

Commentaires:

Anti-Peripherin Antibody is tested for use in Western Blotting, ICC, and IHC. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 57 kDa in size corresponding to peripherin proteins in the appropriate cell lysate or extract. Anti-Peripherin antibody performs well on aldehyde fixed tissues.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Optional[Buffer]: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 ,0.01 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Date de péremption: 12 months

Détails sur Peripherin

Antigène: Peripherin (PRPH)

Autre désignation: Peripherin

Sujet:

Synonyms: NEF4, PRPH1, Peripherin, prph, prph1 antibody, PNS antibodies, monoclonal anti-peripherin, mouse monoclonal antibody to peripherin, monoclonal anti-peripherin antibody produced in mouse

Background: Peripherin Antibody detects Peripherin. Peripherin is a ~57 kDa intermediate filament subunit found initially in sensory neurons of the peripheral nervous systems, which gives the protein its name. Subsequently, peripherin was found in some sensory and other neurons of the central nervous system and also in PC12 cells. Peripherin is also expressed in certain neuroendocrine tumors and in the insulin producing cells of the pancreas. Peripherin belongs to the Class III family of intermediate filament subunits which also includes vimentin, glial fibrillary acidic protein (GFAP) and desmin. In contrast to the neurofilaments, peripherin is strongly up-regulated after nerve injury. Antibodies to peripherin can be used in identifying, classifying, and studying neurons throughout the nervous system. Peripherin is also a good diagnostic marker for ballooned axons seen in Lou Gehrig's disease (Amyotrophic lateral sclerosis) and some neuronally derived tumors. Autoantibodies to peripherin are frequently seen in the sera of patients with diabetes. Peripherin is not related to peripherin/RDS, a protein of the photoreceptor outer membrane mutations of which are causative of certain forms of slow retinal degeneration. Anti-Peripherin Antibody is ideal for investigators involved in Neuroscience and Cancer research.

Gene Name: PRPH

ID gène: 3414

UniProt: P21807