GAP43 anticorps (pSer41)

N° du produit ABIN6658158

N° du produit (Fournisseur): 612-401-d59

Cet anticorps Lapin Polyclonal détecte spécifiquement GAP43 dans WB. Il présente une réactivité envers Rat.

Aperçu rapide pour GAP43 anticorps (pSer41) (ABIN6658158)

Antigène: GAP43 (Growth Associated Protein 43 (GAP43))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GAP43 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GAP43 anticorps

Épitope: pSer41

N° du produit (Fournisseur): 612-401-d59

Fournisseur: Rockland

Fonction: Neuromodulin phospho S41 Antibody

Réactivité croisée (Details): This antibody is specific for the phosphorylated forms of the protein.

Purification: Anti-GAP43 pS41 antibody was affinity purified from monospecific antiserum by immunoaffinity purification.

Immunogène: Anti-Neuromodulin Antibody was produced by repeated immunizations with a synthetic phospho-peptide corresponding to amino acid residues surrounding Ser41 of GAP43.

Isotype: IgG

Information d'application

Indications d'application:

Western_Blot_Dilution: 1:1000

Other: User Optimized

Commentaires:

Anti-GAP43 (Rabbit) antibody is tested for use in Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 50 kDa in size corresponding to neuromodulin protein phosphorylated at Ser41 in the appropriate cell lysate or extract. In some tissues, the antibody also recognized a higher molecular weight protein that may be an aggregate or oligomer.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Date de péremption: 12 months

Détails sur GAP43

Antigène: GAP43 (Growth Associated Protein 43 (GAP43))

Autre désignation: Neuromodulin (GAP43)

Sujet:

Synonyms: Neuromodulin, Axonal membrane protein GAP-43, Growth-associated protein 43, Protein F1, Neural phosphoprotein B-50, pp46

Background: Gap-43 pS41 antibody detects phophorylated GAP43 at position S41. Gap43 is thought to have an important role in development and plasticity because it is expressed at high levels in neuronal growth cones during development and during axonal regeneration. There is also evidence from knockout animals that Gap-43 serves to amplify pathfinding signals from the growth cone. Gap-43 is thought to mediate at least some of these effects via interaction with actin. Importantly, phosphorylation at Ser41 by protein kinase C modulates the interaction of Gap-43 with actin and may also affect eurotransmitter release during forms of plasticity like LTP. Anti-Gap-43 pS41 antibody is ideal for investigators involved in Cell Signaling, Neuroscience, and Signal Transduction research.

Gene Name: GAP43

ID gène: 29423

UniProt: P07936