KCNK3 anticorps (AA 251-411)

N° du produit ABIN6658182

N° du produit (Fournisseur): 200-301-w85

Cet anticorps Souris Monoclonal détecte spécifiquement KCNK3 dans WB, ELISA et IHC. Il présente une réactivité envers Rat.

Aperçu rapide pour KCNK3 anticorps (AA 251-411) (ABIN6658182)

Antigène: KCNK3 (Potassium Channel, Subfamily K, Member 3 (KCNK3))

Reactivité: Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp KCNK3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Clone: S374-48

Détail du produit anti-KCNK3 anticorps

Épitope: AA 251-411

N° du produit (Fournisseur): 200-301-w85

Fournisseur: Rockland

Fonction: TASK1 Potassium Channel Antibody

Réactivité croisée (Details): BLAST analysis suggests that it is 96 % identical to mouse, 76 % identical to human, and <30 % identical to TASK3.

Purification: Anti-TASK1 Potassium Channel Antibody was purified from concentrated tissue culture supernate by Protein G chromatography.

Stérilité: Sterile filtered

Immunogène: Anti-TASK1 Potassium Channel Antibody was produced by repeated immunization of mice with a fusion protein containing amino acids 251-411 of rat TASK1.

Isotype: IgG2b

Information d'application

Indications d'application:

ELISA_Dilution: 1:10,000

Western_Blot_Dilution: 1:1000

Commentaires:

Anti-TASK1 Potassium Channel Antibody is suitable for Western Blots, Immunohistochemistry and Immunocytochemistry. Expect a band approximately ~50kDa on specific lysates or tissues. Does not cross react with TASK3. Specific conditions for reactivity should be optimized by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 50 % (v/v) Glycerol

Preservative: 0.1 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Date de péremption: 12 months

Détails sur KCNK3

Antigène: KCNK3 (Potassium Channel, Subfamily K, Member 3 (KCNK3))

Autre désignation: Kcnk3

Sujet:

Synonyms: Potassium channel subfamily K member 3, KCNK3, Acid sensitive potassium channel protein TASK 1, Cardiac two pore background K(+) channel, cTBAK 1, K2p3.1, KCNK9, OAT1, potassium channel subfamily K member 3, rTASK, TASK 1, TBAK1

Background: K+ channels are divided into three subclasses reflecting the number of transmembrane segments (TMS), which are designated 6TMS, 4TMS and 2TMS. Members of the 4TMS class contain two distinct pore regions and include TWIK, TREK, TRAAK and TASK. TASK channels are highly sensitive to external pH in the physiological range. TASK-1 is expressed in brain and in rat heart, with high levels of expression in the right atrium. TASK-2, mainly expressed in kidney, is localized in cortical distal tubules and collecting ducts, suggesting a role in renal K+ transport. TASK-3 from rat cerebellum shares 54 % identity with TASK-1, but less than 30 % identity with TASK-2 and other tandem pore K+ channels. Anti-TASK1 Potassium Channel Antibody is ideal for research in Neuroscience, particularly studies concerning the dopaminergic neuron and melatonin signaling.

Gene Name: TASK1

ID gène: 29553

NCBI Accession: NP_203694

UniProt: O54912