GABBR1 anticorps (pSer923)

N° du produit ABIN6658230

N° du produit (Fournisseur): 612-401-d54

Cet anticorps Lapin Polyclonal détecte spécifiquement GABBR1 dans WB. Il présente une réactivité envers Rat et a été mentionné dans 1 publication.

Aperçu rapide pour GABBR1 anticorps (pSer923) (ABIN6658230)

Antigène: GABBR1 (gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GABBR1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GABBR1 anticorps

Épitope: pSer923

N° du produit (Fournisseur): 612-401-d54

Fournisseur: Rockland

Fonction: GABA(B) Receptor 1 phospho S923 Antibody

Réactivité croisée (Details): Anti-GABA(B) Receptor 1 pS923 Antibody is directed against rat phosphorylated GABA(B) Receptor .

Purification: The antibody was affinity purified from monospecific antiserum by immunoaffinity purification.

Immunogène: Anti-GABA(B) Receptor 1 pS923 Antibody was produced by repeated immunizations with synthetic phospho-peptide corresponding to amino acid residues surrounding Ser 923 of rat GABA B R1.

Isotype: IgG

Information d'application

Indications d'application: Optional[Neutralization_Dilution]: 1:1000

Commentaires:

Anti-GABA(B) Receptor 1 pS923 (Rabbit) antibody is tested for use in Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 102 kDa in size corresponding to GABA(B) receptor 1 protein phosphorylated at Ser923 in the appropriate cell lysate or extract.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Date de péremption: 12 months

Références pour anticorps anti-GABBR1 (ABIN6658230)

Feng, Gao, Yue, Liu, Zhou, Ren, Teng: "Autophagy-lysosome dysfunction is involved in gastric ischemia-reperfusion injury by promoting microglial activation in the paraventricular nucleus." dans: Journal of biochemical and molecular toxicology, Vol. 36, Issue 2, pp. e22957, (2022) (PubMed).

Détails sur GABBR1

Antigène: GABBR1 (gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1))

Autre désignation: GABA(B) Receptor 1

Sujet:

Synonyms: Gamma-aminobutyric acid type B receptor subunit 1, GABA-B-R1, GABA-BR1, GABABR1, Gb1

Background: GABA(A) Receptor 1 pS923 Antibody detects phosphorylated GABA(A) Receptor gamma 2. Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system. There are two major classes of GABA receptors: the GABAA and the GABAB subtype of receptors. GABAB receptors are heterodimeric G protein-coupled receptors that mediate slow synaptic inhibition in the central nervous system. Phosphorylation enhances GABAB receptor effector coupling. Phosphorylation of Ser 923 is thought to be important in the regulation of GABAB receptor function. GABA(B) Receptor 1 pS923 antibody is ideal for investigators involved in Neuroscience.

Gene Name: GABBR1

ID gène: 81657, 8393403

UniProt: Q9Z0U4

Pathways: Positive Regulation of Peptide Hormone Secretion, cAMP Metabolic Process