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Synaptojanin 1 anticorps (C-Term)

SYNJ1 Reactivité: Rat WB, IHC Hôte: Souris Monoclonal 5H1 unconjugated
N° du produit ABIN6658254
  • Antigène Voir toutes Synaptojanin 1 (SYNJ1) Anticorps
    Synaptojanin 1 (SYNJ1)
    Épitope
    • 15
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 21
    • 17
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Rat
    Hôte
    • 31
    • 4
    Souris
    Clonalité
    • 32
    • 3
    Monoclonal
    Conjugué
    • 17
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Synaptojanin 1 est non-conjugé
    Application
    • 16
    • 13
    • 13
    • 13
    • 4
    • 3
    • 3
    • 3
    • 2
    Western Blotting (WB), Immunohistochemistry (IHC)
    Réactivité croisée (Details)
    Cross reactivity from other species has not been determined.
    Purification
    Anti-Synaptojanin 1 Monoclonal Antibody is directed against rat synaptojanin 1. Synaptojanin 1 antibody was Protein G purified. Immunolabeling blocked by preadsorption of antibody with the protein used to generate the antibody.
    Immunogène

    Immunogen: Anti-Synaptojanin 1 Monoclonal Antibody was produced in mouse by repeated immunizations with recombinant protein from the C-terminal region of rat synaptojanin 1.

    Immunogen Type: Recombinant Protein

    Clone
    5H1
    Isotype
    IgG
    Top Product
    Discover our top product SYNJ1 Anticorps primaire
  • Indications d'application

    Immunohistochemistry Dilution: 1:100

    Application Note: Anti-Synaptojanin 1 antibody is suitable for use in Western Blotting and IHC. Expect a band of approximately 145 kDa in size corresponding to synaptojanin I proteins of rat brain extracts. Researchers should determine optimal titers for applications that are not stated below.

    Western Blot Dilution: 1:1000

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer

    Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

    Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
  • Antigène
    Synaptojanin 1 (SYNJ1)
    Autre désignation
    Synaptojanin 1 (SYNJ1 Produits)
    Synonymes
    anticorps CG6562, anticorps Dmel\\CG6562, anticorps IPP, anticorps Synj, anticorps fb02f11, anticorps fi15a11, anticorps nrc, anticorps wu:fb02f11, anticorps wu:fi15a11, anticorps SYNJ1, anticorps INPP5G, anticorps A930006D20Rik, anticorps AA675315, anticorps mKIAA0910, anticorps Synaptojanin, anticorps synaptojanin 1, anticorps Synj, anticorps synj1, anticorps SYNJ1, anticorps Synj1
    Sujet

    Synonyms: mouse anti-Synaptojanin 1 Antibody, Synaptic inositol-1,4,5-trisphosphate 5-phosphatase 1

    Background: Synaptojanin 1 Monoclonal Antibody detects Synaptojanin 1, which is a phosphatidylinositol phosphatase involved in clathrin-mediated endocytosis of synaptic vesicles. Synaptojanin 1 has two alternatively spliced isoforms, one that is ~ 145 kDA and is exclusively expressed in neurons, and the other ~ 170 kDa which is expressed in non-neuronal, peripheral tissues. The gene which encodes Synaptojanin 1, SYNJ1, has been mapped to chromosome 21 thus making it a candidate for involvement in Down's syndrome (DS). It has recently been demonstrated that Ts65Dn mice (the most commonly used model of DS) have altered phosphatidylinositol-4,5-bisphosphate metabolism. This defect is rescued by restoring SYNJ1 to disomy in the Ts65Dn mice.

    Gene Name: SYNJ1

    ID gène
    85238
    UniProt
    Q62910
    Pathways
    Inositol Metabolic Process, Synaptic Vesicle Exocytosis
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