Clavesin 1 anticorps (C-Term)
Aperçu rapide pour Clavesin 1 anticorps (C-Term) (ABIN6658285)
Antigène
Voir toutes Clavesin 1 (CLVS1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- C-Term
-
N° du produit (Fournisseur)
- 612-401-d17
-
Fournisseur
- Rockland
-
Fonction
- Clavesin Antibody
-
Réactivité croisée (Details)
- Anti-Clavesin antibody is directed against rat Clavesin protein.
-
Purification
- The antibody was affinity purified from monospecific antiserum by immunoaffinity purification.
-
Immunogène
- Anti-Clavesin Antibody was produced in rabbit by repeated immunizations with synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH.
-
Isotype
- IgG
-
-
-
-
Indications d'application
-
ELISA_Dilution: 1:10,000
Western_Blot_Dilution: 1:1000
Other: ICC 1:50
-
Commentaires
-
Anti-Clavesin antibody is tested for use in ELISA, Western Blotting and ICC. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 35 kDa in size corresponding to clavesin protein doublet in Western Blots of rat brain lysate. Isoform-specific knock down in cultured hippocampal neurons indicates that the lower and upper bands are clavesin 1 and 2, respectively.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
-
Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 50 % (v/v) Glycerol
-
Stock
- 4 °C,-20 °C
-
Stockage commentaire
- Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
-
Date de péremption
- 12 months
-
-
- Clavesin 1 (CLVS1)
-
Autre désignation
- Clavesin
-
Sujet
-
Synonyms: Retinaldehyde-binding protein 1-like 1
Background: Clavesin antibody recognizes clavesin (clathrin vesicle associated Sec14 protein) which is a novel neuron specific protein that has recently been identified and shown to be required for normal morphology of late endosomes and/or lysosomes as lentiviral-mediated knockdown of clavesin in hippocampal neurons causes lysosomal defects. Additionally, upregulation of clavesin in human hepatocellular carcinoma has recently been demonstrated thus making it a useful marker for this disease state. Anti-Clavesin antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.
Gene Name: CLVS1/2
-
ID gène
- 366311
-
UniProt
- A6JFQ6
Antigène
-