Clavesin 1 anticorps (C-Term)

N° du produit ABIN6658285

Détail du produit anti-Clavesin 1 anticorps

Antigène: Clavesin 1 (CLVS1)

Épitope: C-Term

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Clavesin 1 est non-conjugé

Application: Western Blotting (WB), ELISA

Réactivité croisée (Details): Cross reactivity with Clavesin from other species has not been determined

Purification: Anti-Clavesin antibody is directed against rat Clavesin protein. The antibody was affinity purified from monospecific antiserum by immunoaffinity purification. . However, reactivity is also expected from the following species based on 100% sequence homology: mouse and human.

Immunogène:

Immunogen: Anti-Clavesin Antibody was produced in rabbit by repeated immunizations with synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH.

Immunogen Type: Peptide

Isotype: IgG

Information d'application

Indications d'application:

Application Note: Anti-Clavesin antibody is suitable for use in ELISA, Western Blotting and ICC. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 35 kDa in size corresponding to clavesin protein doublet in Western Blots of rat brain lysate. Isoform-specific knock down in cultured hippocampal neurons indicates that the lower and upper bands are clavesin 1 and 2, respectively.

ELISA Dilution: 1:10,000

Western Blot Dilution: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 50 % (v/v) Glycerol

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Détails sur Clavesin 1

Antigène: Clavesin 1 (CLVS1)

Autre désignation: Clavesin (CLVS1 Produits)

Synonymes: anticorps RLBP1L1, anticorps rlbp1l1, anticorps CRALBPL, anticorps 4933402J24Rik, anticorps Clvl1, anticorps Rlbp1l1, anticorps Clavesin-1, anticorps RGD1564200, anticorps clavesin 1, anticorps clavesin 1 L homeolog, anticorps CLVS1, anticorps clvs1.L, anticorps Clvs1

Sujet:

Synonyms: Retinaldehyde-binding protein 1-like 1

Background: Clavesin antibody recognizes clavesin (clathrin vesicle associated Sec14 protein) which is a novel neuron specific protein that has recently been identified and shown to be required for normal morphology of late endosomes and/or lysosomes as lentiviral-mediated knockdown of clavesin in hippocampal neurons causes lysosomal defects. Additionally, upregulation of clavesin in human hepatocellular carcinoma has recently been demonstrated thus making it a useful marker for this disease state. Anti-Clavesin antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.

Gene Name: CLVS1/2

ID gène: 366311

UniProt: A6JFQ6