MOG anticorps (PE-Cy7)

N° du produit ABIN668494

Cet anticorps Lapin Polyclonal détecte spécifiquement MOG dans FACS. Il présente une réactivité envers Humain, Souris, Rat, Porc et Cobaye.

Aperçu rapide pour MOG anticorps (PE-Cy7) (ABIN668494)

Antigène: MOG (Myelin Oligodendrocyte Glycoprotein (MOG))

Reactivité: Humain, Souris, Rat, Porc, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MOG est conjugé à/à la PE-Cy7

Application: Flow Cytometry (FACS)

Détail du produit anti-MOG anticorps (PE-Cy7)

Specificité: Excitation / Emission Wavelengths: 480,565,743nm/767nm

Réactivité croisée: Rat (Rattus), Porc, Cobaye

Purification: purified by Protein A

Immunogène: KLH conjugated synthetic peptide derived from human MOG

Isotype: IgG

Information d'application

Indications d'application: FCM(1:100-500)
Optimal working dilution should be determined by the investigator.

Commentaires:

Excitation / Emission wavelength: 496,565nm / 774nm

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 µg/µL

Buffer: Aqueous buffered solution containing 100 µg/mL BSA, 50 % glycerol and 0.09 % Gentamicin.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 4 °C for 12 months

Date de péremption: 12 months

Détails sur MOG

Antigène: MOG (Myelin Oligodendrocyte Glycoprotein (MOG))

Autre désignation: MOG

Sujet: Myelin oligodendrocyte glycoprotein (MOG) is a key CNS-specific autoantigen for primary demyelination in multiple sclerosis. Although the disease-inducing role of MOG has been established, its precise function in the CNS remains obscure. MOG is a type I integral membrane protein possessing a single extracellular Ig variable domain (Ig-V) (3, 13, 14). The amino acid sequence of MOG is highly conserved among animal species (>90%), indicative of an important biological function. MOG is specifically expressed in the CNS on the outermost lamellae of the myelin sheath as well as the cell body and processes of oligodendrocytes. The developmentally late expression of MOG correlates with the later stages of myelinogenesis, suggesting that MOG has a role in the completion, compaction, and/or maintenance of myelin, further suggesting that MOG has an adhesive function within the CNS . Consistent with MOG's possible adhesive role in the CNS, a homodimeric form of MOG has not only been observed after isolation from the CNS but has additionally been observed in situ.

Poids moléculaire: 28kDa

ID gène: 4340