TXN anticorps (AA 51-105)

N° du produit ABIN668871

Cité dans 3 publications. Cet anticorps anti-TXN Polyclonal Lapin (ABIN668871) détecte spécifiquement TXN dans ICC, FACS, IF, IHC (p) et IHC (fro). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour TXN anticorps (AA 51-105) (ABIN668871)

Antigène: TXN (Thioredoxin (TXN))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TXN est non-conjugé

Application: Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-TXN anticorps

Épitope: AA 51-105

Fonction: Thioredoxin Polyclonal Antibody

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Thioredoxin

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-TXN (ABIN668871)

Zhang, Hu, Guo, Wang, Zhao, Zhang, Yang, Yu, Niu, Yang, Zheng, Wang: "Screening and identification of post-traumatic stress-related serum factors in children with Wilms' tumors." dans: Oncology letters, Vol. 11, Issue 2, pp. 1299-1304, (2016) (PubMed).

Gao, Yuan, Gao, Cai, Zhu, Liu, Wang, Wei, Huang, Liang, Gao: "Cytotoxicity and therapeutic effect of irinotecan combined with selenium nanoparticles." dans: Biomaterials, Vol. 35, Issue 31, pp. 8854-66, (2014) (PubMed).

Li, Sun, Xiao, Sun: "First characterization of a teleost Epstein-Barr virus-induced gene 3 (EBI3) reveals a regulatory effect of EBI3 on the innate immune response of peripheral blood leukocytes." dans: Developmental and comparative immunology, Vol. 41, Issue 4, pp. 514-22, (2013) (PubMed).

Détails sur TXN

Antigène: TXN (Thioredoxin (TXN))

Autre désignation: Thioredoxin

Sujet:

Synonyms: TRX, TRDX, TRX1, Thioredoxin, ATL-derived factor, ADF, Surface-associated sulphydryl protein, SASP, TXN

Background: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity. ADF augments the expression of the interleukin-2 receptor TAC (IL2R/P55).

ID gène: 7295

UniProt: P10599

Pathways: Carbohydrate Homeostasis, Cell RedoxHomeostasis