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tau anticorps (PE)

Reactivité: Humain, Souris WB, ELISA Hôte: Lapin Polyclonal PE
N° du produit ABIN6698782
  • Antigène Voir toutes tau Anticorps
    tau (tau Protein)
    Reactivité
    • 524
    • 501
    • 498
    • 40
    • 28
    • 27
    • 18
    • 6
    • 3
    • 2
    • 1
    • 1
    Humain, Souris
    Hôte
    • 629
    • 36
    • 2
    • 1
    Lapin
    Clonalité
    • 604
    • 63
    • 1
    Polyclonal
    Conjugué
    • 209
    • 40
    • 34
    • 33
    • 33
    • 33
    • 32
    • 32
    • 32
    • 30
    • 24
    • 24
    • 24
    • 24
    • 24
    • 12
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    Cet anticorp tau est conjugé à/à la PE
    Application
    • 548
    • 272
    • 263
    • 204
    • 92
    • 85
    • 68
    • 59
    • 53
    • 36
    • 34
    • 16
    • 12
    • 12
    • 12
    • 9
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    Specificité
    Detects ~45.8kda.
    Purification
    Protein A Purified
    Immunogène
    Synthetic peptide from the full length of Human Tau
    Top Product
    Discover our top product tau Anticorps primaire
  • Indications d'application
    • WB (1:1000)
    • optimal dilutions for assays should be determined by the user.
    • optimal dilutions for assays should be determined by the user.
    Commentaires

    A 1:1000 dilution of ABIN6698782 was sufficient for detection of Tau in 10 μg of human SH-SY5Y cell lysate cell lysates by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS pH 7.4, 50 % glycerol, 0.09 % Sodium Azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
  • Antigène
    tau (tau Protein)
    Autre désignation
    Tau (tau Produits)
    Synonymes
    anticorps DDPAC, anticorps FTDP-17, anticorps MAPTL, anticorps MSTD, anticorps MTBT1, anticorps MTBT2, anticorps PPND, anticorps TAU, anticorps tau, anticorps PHF-tau, anticorps microtubule associated protein tau, anticorps MAPT
    Sujet
    Alzheimer's Disease (AD) is the most common neurodegenerative disease, affecting 10 % of seniors over the age of 65 (1). It was named after Alois Alzheimer, a German scientist who discovered tangled bundles of fibrils where neurons had once been in the brain of a deceased patient in 1907 (2). Tau (tubulin-associated unit) is normally located in the axons of neurons where it stabilizes microtubules. Tauopathies such as AD are characterized by neurofibrillary tangles containing hyperphosphorylated tau fibrils (3). There are six isoforms of tau in the adult human brain: three with four repeat units (4R) and three with three repeat units (3R) (4). K18 is a truncated form of human tau containing only the 4 microtubule binding repeats (5). P301L (PL) is a mutation where proline is replaced by leucine at codon 301 of tau, and has been linked to frontotemporal dementia (6).
    ID gène
    4137
    UniProt
    P10636
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