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Multidrug-Resistance Like Protein 1 anticorps (AA 501-600)

Cet anticorps anti-Multidrug-Resistance Like Protein 1 est un anticorps Lapin Polyclonal détectant Multidrug-Resistance Like Protein 1 dans WB, FACS, IF (cc), IF (p), ELISA, IHC (p) et IHC (fro). Adapté pour Humain et Rat. Ce Primary Antibody a été cité dans 3+ publications.
N° du produit ABIN671526

Aperçu rapide pour Multidrug-Resistance Like Protein 1 anticorps (AA 501-600) (ABIN671526)

Antigène

Multidrug-Resistance Like Protein 1 (MRP)

Reactivité

  • 32
  • 19
  • 6
Humain, Rat

Hôte

  • 31
  • 4
  • 1
Lapin

Clonalité

  • 24
  • 12
Polyclonal

Conjugué

  • 11
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp Multidrug-Resistance Like Protein 1 est non-conjugé

Application

  • 24
  • 15
  • 12
  • 12
  • 8
  • 8
  • 7
  • 4
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Épitope

    • 15
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 501-600

     Réactivité croisée

    Humain, Rat

    Homologie

    Mouse,Cow,Chicken

    Purification

    Purified by Protein A.

    Immunogène

    KLH conjugated synthetic peptide derived from mouse MRP1

    Isotype

    IgG
  • Indications d'application

    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 μg/μL

    Buffer

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    Agent conservateur

    ProClin

    Précaution d'utilisation

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    Date de péremption

    12 months
  • Peng, Feng, Yuan, Benhabbour, Mumper: "Development of a novel orthotopic non-small cell lung cancer model and therapeutic benefit of 2'-(2-bromohexadecanoyl)-docetaxel conjugate nanoparticles." dans: Nanomedicine : nanotechnology, biology, and medicine, Vol. 10, Issue 7, pp. 1497-506, (2014) (PubMed).

    Yan, Xie, Li, Zhang, Ma, Xie, Li, Zhong: "Epithelial-to-mesenchymal transition is involved in BCNU resistance in human glioma cells." dans: Neuropathology : official journal of the Japanese Society of Neuropathology, (2013) (PubMed).

    Hu, Peng, Li: "The expression and significance of P-glycoprotein, lung resistance protein and multidrug resistance-associated protein in gastric cancer." dans: Journal of experimental & clinical cancer research : CR, Vol. 28, pp. 144, (2009) (PubMed).

  • Antigène

    Multidrug-Resistance Like Protein 1 (MRP)

    Autre désignation

    MRP1

    Sujet

    Synonyms: MRP, Mrp1, Mdrap, Abcc1a, Abcc1b, Multidrug resistance-associated protein 1, ATP-binding cassette sub-family C member 1, Leukotriene C(4) transporter, LTC4 transporter, Abcc1

    Background: Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o-glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs. Hydrolyzes ATP with low efficiency.

    ID gène

    17250

    UniProt

    O35379
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