CCBP2 anticorps (AA 138-384)

N° du produit ABIN6719286

Détail du produit anti-CCBP2 anticorps

Antigène: CCBP2 (Chemokine Binding Protein 2 (CCBP2))

Épitope: AA 138-384

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CCBP2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for D6/ACKR2 detection. Tested with WB, IHC-P, Direct ELISA in Human.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for D6/ACKR2 detection. Tested with WB, IHC-P, Direct ELISA in Human.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human D6/ACKR2 recombinant protein (Position: M138-A384).

Isotype: IgG

Information d'application

Indications d'application:

Application details: Western blot|0.1-0.5 μg/mL Immunohistochemistry(Paraffin-embedded Section)|0.5-1 μg/mL Direct ELISA|0.1-0.5 μg/mL

Commentaires:

Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur CCBP2

Antigène: CCBP2 (Chemokine Binding Protein 2 (CCBP2))

Autre désignation: ACKR2 (CCBP2 Produits)

Synonymes: anticorps CCBP2, anticorps CCR10, anticorps CCR9, anticorps CMKBR9, anticorps D6, anticorps hD6, anticorps Ccbp2, anticorps LOC733624, anticorps A130091K22Rik, anticorps Cmkbr10, anticorps GPR-9-6, anticorps AI464239, anticorps Cmkbr9, anticorps atypical chemokine receptor 2, anticorps atypical chemokine receptor 2-like, anticorps chemokine receptor D6, anticorps chemokine (C-C motif) receptor 9, anticorps C-C motif chemokine receptor 9, anticorps ACKR2, anticorps Ackr2, anticorps LOC100219492, anticorps LOC733624, anticorps Ccr9, anticorps CCR9

Sujet:

Synonyms: Atypical chemokine receptor 2, C-C chemokine receptor D6, Chemokine receptor CCR-10, Chemokine receptor CCR-9, Chemokine-binding protein 2, Chemokine-binding protein D6, ACKR2, CCBP2, CCR10, CMKBR9, D6

Background: This gene encodes a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site. This gene is expressed in a range of tissues and hemopoietic cells. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members, however, its specific function remains unknown. This gene is mapped to chromosome 3p21.3, a region that includes a cluster of chemokine receptor genes.

ID gène: 1238

UniProt: O00590