PON1 anticorps (AA 30-274)
Aperçu rapide pour PON1 anticorps (AA 30-274) (ABIN7354529)
Antigène
Voir toutes PON1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 30-274
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Fonction
- Rabbit IgG polyclonal antibody for PON1 detection. Tested with ELISA(Det) in Mouse.
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Réactivité croisée (Details)
- No cross reactivity with other proteins.
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Attributs du produit
- Rabbit IgG polyclonal antibody for PON1 detection. Tested with ELISA(Det) in Mouse.
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Purification
- Immunogen affinity purified.
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Immunogène
- E. coli-derived mouse PON1 recombinant protein (Position: A30-D274).
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Isotype
- IgG
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Indications d'application
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Application details: ELISA(Det)|0.1-0.5 μg/mL
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Commentaires
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Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- PON1 (Paraoxonase 1 (PON1))
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Autre désignation
- Pon1
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Sujet
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Synonyms: Serum paraoxonase/arylesterase 1, PON 1
Background: Serum paraoxonase/arylesterase 1 (PON1), also known as aromatic esterase 1, is an enzyme that in humans is encoded by the PON1 gene. It is mapped to 7q21.3. This gene has esterase and more specifically paraoxonase activity. PON1 is responsible for hydrolysing organophosphate pesticides and nerve gasses. Polymorphisms in the PON1 gene significantly affect the catalytic ability of the enzyme. PON1 (paraoxonase 1) is also a major anti-atherosclerotic component of high-density lipoprotein (HDL). The PON1 gene is activated by PPAR-γ, which increases synthesis and release of paraoxonase 1 enzyme from the liver, reducing atherosclerosis.
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ID gène
- 18979
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UniProt
- P52430
Antigène
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