RP2 anticorps (AA 244-348)

N° du produit ABIN6719513

Détail du produit anti-RP2 anticorps

Antigène: RP2 (Retinitis Pigmentosa 2 (X-Linked Recessive) (RP2))

Épitope: AA 244-348

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RP2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for RP2 detection. Tested with WB, IHC-P, Direct ELISA in Human,Mouse,Rat.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for RP2 detection. Tested with WB, IHC-P, Direct ELISA in Human,Mouse,Rat.

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived human RP2 recombinant protein (Position: D244-M348).

Isotype: IgG

Information d'application

Indications d'application:

Application details: Western blot|0.1-0.5 μg/mL Immunohistochemistry(Paraffin-embedded Section)|0.5-1 μg/mL Direct ELISA|0.1-0.5 μg/mL

Commentaires:

Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur RP2

Antigène: RP2 (Retinitis Pigmentosa 2 (X-Linked Recessive) (RP2))

Autre désignation: RP2 (RP2 Produits)

Synonymes: anticorps Rp2h, anticorps RGD1565124, anticorps RP2, anticorps wu:fj10e02, anticorps wu:fm72d05, anticorps zfrp2, anticorps zgc:55632, anticorps DELXp11.3, anticorps NM23-H10, anticorps NME10, anticorps TBCCD2, anticorps XRP2, anticorps AI662636, anticorps Rp2, anticorps RP2, ARL3 GTPase activating protein, anticorps XRP2 protein, anticorps XRP2-like protein, anticorps retinitis pigmentosa 2 (X-linked recessive), anticorps RP2, ARL3 GTPase activating protein S homeolog, anticorps retinitis pigmentosa 2 homolog, anticorps Rp2, anticorps RP2, anticorps Bm1_36735, anticorps PITG_13367, anticorps LOAG_11813, anticorps rp2, anticorps rp2.S

Sujet:

Synonyms: Protein XRP2, RP2

Background: Protein XRP2 is a protein that in humans is encoded by the RP2 gene. It is mapped to Xp11.3. The RP2 locus has been implicated as one cause of X-linked retinitis pigmentosa. The predicted gene product shows homology with human cofactor C, a protein involved in the ultimate step of beta-tubulin folding. Progressive retinal degeneration may therefore be due to the accumulation of incorrectly folded photoreceptor or neuron-specific tubulin isoforms followed by progressive cell death. The RP2 protein is also involved in regulating the function and extension of outer segment of cone photoreceptors in mice.

ID gène: 6102

UniProt: O75695

Pathways: Nucleotide Phosphorylation, Ribonucleoside Biosynthetic Process