LONP1 anticorps (AA 137-320)

N° du produit ABIN6719543

Détail du produit anti-LONP1 anticorps

Antigène: LONP1 (Lon Peptidase 1, Mitochondrial (LONP1))

Épitope: AA 137-320

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LONP1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for LONP1/Lon detection. Tested with WB, IHC-P, Direct ELISA in Human,Mouse,Rat.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for LONP1/Lon detection. Tested with WB, IHC-P, Direct ELISA in Human,Mouse,Rat.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human LONP1/Lon recombinant protein (Position: R137-A320).

Isotype: IgG

Information d'application

Indications d'application:

Application details: Western blot|0.1-0.5 μg/mL Immunohistochemistry(Paraffin-embedded Section)|0.5-1 μg/mL Direct ELISA|0.1-0.5 μg/mL

Commentaires:

Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur LONP1

Antigène: LONP1 (Lon Peptidase 1, Mitochondrial (LONP1))

Autre désignation: LONP1 (LONP1 Produits)

Synonymes: anticorps PRSS15, anticorps prss15, anticorps fc64d11, anticorps wu:fc64d11, anticorps LON, anticorps LONP, anticorps LonHS, anticorps PIM1, anticorps hLON, anticorps 1200017E13Rik, anticorps Prss15, anticorps Lon, anticorps lon peptidase 1, mitochondrial, anticorps ATP-dependent Lon protease, anticorps LONP1, anticorps lonp1, anticorps Lonp1, anticorps PIM1

Sujet:

Synonyms: Lon protease homolog, mitochondrial, LONHs, Lon protease-like protein, LONP, Mitochondrial ATP-dependent protease Lon, Serine protease 15, LONP1, PRSS15

Background: Lon protease homolog, mitochondrial is an enzyme that in humans is encoded by the LONP1 gene. It is mapped to 19p13.3. This gene encodes a mitochondrial matrix protein that belongs to the Lon family of ATP-dependent proteases. This protein mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides in the mitochondrial matrix. It may also have a chaperone function in the assembly of inner membrane protein complexes, and participate in the regulation of mitochondrial gene expression and maintenance of the integrity of the mitochondrial genome. Decreased expression of this gene has been noted in a patient with hereditary spastic paraplegia.

ID gène: 9361

UniProt: P36776