CCL8 anticorps (AA 24-97)

N° du produit ABIN6719605

Détail du produit anti-CCL8 anticorps

Antigène: CCL8 (Chemokine (C-C Motif) Ligand 8 (CCL8))

Épitope: AA 24-97

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CCL8 est non-conjugé

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for CCL8 detection. Tested with IHC-P, ELISA(Cap) in Mouse,Rat.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for CCL8 detection. Tested with IHC-P, ELISA(Cap) in Mouse,Rat.

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived mouse CCL8 recombinant protein (Position: G24-P97).

Isotype: IgG

Information d'application

Indications d'application:

Application details: Immunohistochemistry(Paraffin-embedded Section)|0.5-1 μg/mL ELISA(Cap)|1-5 μg/mL

Commentaires:

Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur CCL8

Antigène: CCL8 (Chemokine (C-C Motif) Ligand 8 (CCL8))

Autre désignation: Ccl8 (CCL8 Produits)

Synonymes: anticorps HC14, anticorps MCP-2, anticorps MCP2, anticorps SCYA10, anticorps SCYA8, anticorps 1810063B20Rik, anticorps AB023418, anticorps Mcp2, anticorps Scya8, anticorps C-C motif chemokine ligand 8, anticorps chemokine (C-C motif) ligand 8, anticorps C-C motif chemokine 8, anticorps monocyte chemoattractant protein-2 precursor, anticorps CCL8, anticorps Ccl8, anticorps LOC101119572, anticorps MCP-2

Sujet:

Synonyms: C-C motif chemokine 8, Monocyte chemoattractant protein 2, Monocyte chemotactic protein 2, MCP-2, Small-inducible cytokine A8, Ccl8, Mcp2, Scya8

Background: CCL8, also known as monocyte chemoattractant protein 2 (MCP2), is a protein that in humans is encoded by the CCL8 gene. It is a small cytokine belonging to the CC chemokine family. The CCL8 protein is produced as a precursor containing 109 amino acids, which is cleaved to produce mature CCL8 containing 75 amino acids. The gene for CCL8 is encoded by 3 exons and is located within a large cluster of CC chemokines on chromosome 17q11.2 in humans. MCP-2 is chemotactic for and activates many different immune cells, including mast cells, eosinophils and basophils, (that are implicated in allergic responses), and monocytes, T cells, and NK cells that are involved in the inflammatory response. CCL8 elicits its effects by binding to several different cell surface receptors called chemokine receptors. These receptors include CCR1, CCR2B, CCR3 and CCR5.

ID gène: 20307

UniProt: Q9Z121