PDCD10 anticorps (AA 1-212) (DyLight 550)

N° du produit ABIN7354691

Cet anticorps Lapin Polyclonal détecte spécifiquement PDCD10 dans FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour PDCD10 anticorps (AA 1-212) (DyLight 550) (ABIN7354691)

Antigène: PDCD10 (Programmed Cell Death 10 (PDCD10))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDCD10 est conjugé à/à la DyLight 550

Application: Flow Cytometry (FACS)

Détail du produit anti-PDCD10 anticorps (DyLight 550)

Épitope: AA 1-212

Fonction: Anti-Human PDCD10 DyLight® 550 conjugated Antibody

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-Human PDCD10 DyLight® 550 conjugated Antibody -Dyl550. Tested in Flow Cytometry applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived human PDCD10 recombinant protein (Position: M1-A212).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells1. "Entrez Gene: PDCD10 programmed cell death 10". 2. Bergametti F, Denier C, Labauge P, Arnoult M, Boetto S, Clanet M, Coubes P, Echenne B, Ibrahim R, Irthum B, Jacquet G, Lonjon M, Moreau JJ, Neau JP, Parker F, Tremoulet M, Tournier-Lasserve E (Jan 2005). "Mutations within the programmed cell death 10 gene cause cerebral cavernous malformations". American Journal of Human Genetics. 76 (1): 42-51.

Commentaires:

Other applications have not been tested. Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Détails sur PDCD10

Antigène: PDCD10 (Programmed Cell Death 10 (PDCD10))

Autre désignation: PDCD10

Sujet:

Synonyms: Programmed cell death protein 10, Cerebral cavernous malformations 3 protein, TF-1 cell apoptosis-related protein 15, PDCD10, CCM3, TFAR15

Tissue Specificity: Ubiquitous.

Background: Programmed cell death protein 10 is a protein that in humans is encoded by the PDCD10 gene. This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Poids moléculaire: 39 kDa

ID gène: 11235