TDRD3 anticorps

N° du produit ABIN6719636

L’anticorps Lapin Polyclonal anti-TDRD3 a été validé pour WB, IF et IHC. Il convient pour détecter TDRD3 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour TDRD3 anticorps (ABIN6719636)

Antigène: TDRD3 (Tudor Domain Containing 3 (TDRD3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TDRD3 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)

Détail du produit anti-TDRD3 anticorps

Fonction: Anti-TDRD3 Antibody Picoband®

Séquence: KPTNDNDEFE KQRTAAIAEV AKSKETK

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-TDRD3 Antibody Picoband® (ABIN6719636). Tested in IF, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human TDRD3, which shares 96.3% and 100% amino acid (aa) sequence identity with mouse and rat TDRD3, respectively.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
Immunofluorescence, 2 μg/mL
1. Goulet, Boisvenue, S., Mokas, S., Mazroui, R., Cote, J. TDRD3, a novel tudor domain-containing protein, localizes to cytoplasmic stress granules. Hum. Molec. Genet. 17: 3055-3074, 2008.  2. Linder, B., Plottner, O., Kroiss, M., Hartmann, E., Laggerbauer, B., Meister, G., Keidel, E., Fischer, U. Tdrd3 is a novel stress granule-associated protein interacting with the fragile-X syndrome protein FMRP. Hum. Molec. Genet. 17: 3236-3246, 2008.

Commentaires:

Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur TDRD3

Antigène: TDRD3 (Tudor Domain Containing 3 (TDRD3))

Autre désignation: TDRD3

Sujet:

Synonyms: Tudor domain-containing protein 3, TDRD3

Tissue Specificity: Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.

Background: Tudor domain-containing protein 3 is a protein that in humans is encoded by the TDRD3 gene. This gene is mapped to 13q21.2. It contains a Tudor domain and UBA protein domain and has three distinct Protein isoforms. TDRD3 is a multifunctional protein that acts as a transcriptional coactivator in the nucleus and as a scaffolding protein in cytoplasmic stress granules.

Poids moléculaire: 65-73 kDa

ID gène: 81550

UniProt: Q9H7E2