MSTN anticorps (AA 281-375)

N° du produit ABIN674469

Cet anticorps anti-MSTN est un anticorps Lapin Polyclonal détectant MSTN dans WB, ELISA, IF (cc), IF (p), IHC (p) et IHC (fro). Adapté pour Humain, Souris, Rat et Porc. Ce Primary Antibody a été cité dans 2+ publications.

Aperçu rapide pour MSTN anticorps (AA 281-375) (ABIN674469)

Antigène: MSTN (Myostatin (MSTN))

Reactivité: Humain, Souris, Rat, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MSTN est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-MSTN anticorps

Épitope: AA 281-375

Réactivité croisée: Humain, Souris, Porc, Rat

Homologie: Cow,Sheep,Horse,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human GDF8

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-MSTN (ABIN674469)

Qian, Tang, Yang, Wang, Cai, Jiang, Li, Jiang, Gao, Ma, Chen, An, Li, Cui: "Targeted mutations in myostatin by zinc-finger nucleases result in double-muscled phenotype in Meishan pigs." dans: Scientific reports, Vol. 5, pp. 14435, (2016) (PubMed).

Détails sur MSTN

Antigène: MSTN (Myostatin (MSTN))

Autre désignation: GDF8/MSTN

Sujet:

Synonyms: GDF8, MSLHP, Growth/differentiation factor 8, GDF-8, Myostatin, MSTN

Background: The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. This gene is thought to encode a secreted protein which negatively regulates skeletal muscle growth. Acts specifically as a negative regulator of skeletal muscle growth. [SUBUNIT] Homodimer, [TISSUE SPECIFICITY] Expressed specifically in developing and adult skeletal muscle. Weak expression in adipose tissue. Belongs to the TGF-beta family.

ID gène: 2660

UniProt: O14793