COCH anticorps (AA 141-190)

N° du produit ABIN6746617

Cet anticorps anti-COCH est un anticorps Lapin Polyclonal détectant COCH dans WB. Adapté pour Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Lapin et Singe. Ce Primary Antibody a été cité dans 4+ publications.

Aperçu rapide pour COCH anticorps (AA 141-190) (ABIN6746617)

Antigène: COCH (Cochlin (COCH))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Lapin, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp COCH est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-COCH anticorps

Épitope: AA 141-190

Specificité: Human COCH

Homologie: Percent identity by BLAST analysis: Human, Mouse, Rat, Dog, Bovine, Rabbit, Guinea pig (100%) Horse (92%) Chicken (85%).

Purification: Immunoaffinity purified

Immunogène: Synthetic peptide located between aa141-190 of human COCH (O43405, NP_001128530). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Dog, Bovine, Rabbit, Guinea pig (100%), Elephant, Panda, Horse (92%), Bat, Opossum, Chicken, Platypus, Lizard, Xenopus (85%).

Type of Immunogen: Synthetic peptide

Information d'application

Indications d'application: Approved: WB (0.2 - 1 μg/mL)

Usage: Western Blot: Suggested dilution at 0.25 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Distilled water

Concentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

Références pour anticorps anti-COCH (ABIN6746617)

Anfosso, Bardin, Francès, Vivier, Camoin-Jau, Sampol, Dignat-George: "Activation of human endothelial cells via S-endo-1 antigen (CD146) stimulates the tyrosine phosphorylation of focal adhesion kinase p125(FAK)." dans: The Journal of biological chemistry, Vol. 273, Issue 41, pp. 26852-6, (1998) (PubMed).

Jean, Gershenwald, Huang, Luca, Hudson, Tainsky, Bar-Eli: "Loss of AP-2 results in up-regulation of MCAM/MUC18 and an increase in tumor growth and metastasis of human melanoma cells." dans: The Journal of biological chemistry, Vol. 273, Issue 26, pp. 16501-8, (1998) (PubMed).

Xie, Luca, Huang, Gutman, Reich, Johnson, Bar-Eli: "Expression of MCAM/MUC18 by human melanoma cells leads to increased tumor growth and metastasis." dans: Cancer research, Vol. 57, Issue 11, pp. 2295-303, (1997) (PubMed).

Lehmann, Riethmüller, Johnson: "MUC18, a marker of tumor progression in human melanoma, shows sequence similarity to the neural cell adhesion molecules of the immunoglobulin superfamily." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 86, Issue 24, pp. 9891-5, (1990) (PubMed).

Détails sur COCH

Antigène: COCH (Cochlin (COCH))

Autre désignation: Cochlin / COCH

Sujet: Name/Gene ID: COCH

Synonyms: COCH, COCH5B2, COCH-5B2, Cochlin, DFNA9, DFNA31

ID gène: 1690

NCBI Accession: NP_001128530

UniProt: O43405

Pathways: Sensory Perception of Sound