CD51/CD61 anticorps (Biotin)

N° du produit ABIN674786

L’anticorps Lapin Polyclonal anti-CD51/CD61 a été validé pour WB, IHC (fro), ELISA et IHC (p). Il convient pour détecter CD51/CD61 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour CD51/CD61 anticorps (Biotin) (ABIN674786)

Antigène: CD51/CD61 (ITGAV/ITGB3) (Integrin alpha V, Integrin beta 3 (ITGAV/ITGB3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD51/CD61 est conjugé à/à la Biotin

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-CD51/CD61 anticorps (Biotin)

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Integrin Alpha V + Beta 3

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur CD51/CD61

Antigène: CD51/CD61 (ITGAV/ITGB3) (Integrin alpha V, Integrin beta 3 (ITGAV/ITGB3))

Autre désignation: Integrin Alpha V + Beta 3

Sujet:

Synonyms: CD51, MSK8, VNRA, VTNR, Integrin alpha-V, Vitronectin receptor subunit alpha, ITGAV, CD61, GP3A, BDPLT2, GPIIIa, BDPLT16, Integrin beta-3, Platelet membrane glycoprotein IIIa, ITGB3

Background: ITAGV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, that combine with multiple integrin beta chains to form different integrins. Among the known associating beta chains (beta chains 1,3,5,6, and 8, 'ITGB1', 'ITGB3', 'ITGB5', 'ITGB6', and 'ITGB8'), each can interact with extracellular matrix ligands, the alpha V beta 3 integrin, perhaps the most studied of these, is referred to as the Vitronectin receptor (VNR). In addition to adhesion, many integrins are known to facilitate signal transduction. The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling.

ID gène: 3690, 3685

UniProt: P05106, P06756