Hemagglutinin anticorps

N° du produit ABIN676553

L’anticorps anti-Hemagglutinin Polyclonal Lapin est utilisé pour la détection de Hemagglutinin dans des échantillons de Influenza A Virus H1N1. Il a été validé pour ELISA, WB, IF (p), IF (cc), IHC (p) et IHC (fro).

Aperçu rapide pour Hemagglutinin anticorps (ABIN676553)

Antigène: Hemagglutinin (HA)

Reactivité: Influenza A Virus H1N1

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Hemagglutinin est non-conjugé

Application: ELISA, Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-Hemagglutinin anticorps

Virus Strain: A/California/04/2009

Réactivité croisée: Virus

Réactivité croisée (Details): Influenza A virus H1N1 (strain swl A/California/04/2009 H1N1)

Attributs du produit: Antibody is specific for: Influenza A virus H1N1 (strain swl A/California/04/2009 H1N1)

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from Influenza A Virus Hemagglutinin (strain swl A/California/04/2009 H1N1)

Isotype: IgG

Information d'application

Indications d'application: WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur Hemagglutinin

Antigène: Hemagglutinin (HA)

Classe de substances: Influenza Protein

Sujet:

Synonyms: HA, HA2, Hemagglutinin, Influenza A Virus (strain swl A/California/04/2009 H1N1)

Background: Influenza A virus is a major public health threat. Novel influenza virus strains caused by genetic drift and viral recombination emerge periodically to which humans have little or no immunity, resulting in devastating pandemics. Influenza A can exist in a variety of animals, however it is in birds that all subtypes can be found. These subtypes are classified based on the combination of the virus coat glycoproteins hemagglutinin (HA) and neuraminidase (NA) subtypes. HA interacts with cell surface proteins containing oligosaccharides with terminal sialyl residues. Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization of about two third of the virus particles through clathrin-dependent endocytosis and about one third through a clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore. Influenza A Virus (strain swl A/California/04/2009 H1N1)

UniProt: C3W5S1