ITGAV/ITGB1 anticorps (PE-Cy7)

N° du produit ABIN676731

Cet anticorps anti-ITGAV/ITGB1 Polyclonal Lapin conjugué à PE-Cy7 (ABIN676731) détecte spécifiquement ITGAV/ITGB1 dans WB et FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour ITGAV/ITGB1 anticorps (PE-Cy7) (ABIN676731)

Antigène: ITGAV/ITGB1 (Integrin alpha V, Integrin beta 1 (ITGAV/ITGB1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ITGAV/ITGB1 est conjugé à/à la PE-Cy7

Application: Western Blotting (WB), Flow Cytometry (FACS)

Détail du produit anti-ITGAV/ITGB1 anticorps (PE-Cy7)

Fonction: Integrin Alpha V + Beta 1 Polyclonal Antibody, PE-Cy7 Conjugated

Réactivité croisée: Humain, Rat

Homologie: Mouse,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogène: Mixed KLH conjugated syntheticpeptides for human Integrin Alpha V and human Integrin Beta1

Isotype: IgG

Information d'application

Indications d'application: WB(1:300-5000), FCM(1:20-100)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur ITGAV/ITGB1

Antigène: ITGAV/ITGB1 (Integrin alpha V, Integrin beta 1 (ITGAV/ITGB1))

Sub Type: Cocktail

Sujet:

Synonyms: Integrin alpha-V: Integrin alpha-V, Vitronectin receptor subunit alpha, CD51 Integrin beta-1: Fibronectin receptor subunit beta, Glycoprotein IIa, GPIIA, VLA-4 subunit beta, CD29

Background: The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. Integrin alpha-V/beta-1 is a receptor for vitronectin. Beta-1 integrins recognize the sequence R-G-D in a wide array of ligands. Isoform 2 interferes with isoform 1 resulting in a dominant negative effect on cell adhesion and migration (in vitro).

Poids moléculaire: 114kDa

ID gène: 3685