Enkephalin anticorps

N° du produit ABIN677633

L’anticorps Lapin Polyclonal anti-Enkephalin a été validé pour IHC (p). Il convient pour détecter Enkephalin dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Enkephalin anticorps (ABIN677633)

Antigène: Enkephalin (PENK) (Proenkephalin (PENK))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Enkephalin est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Enkephalin anticorps

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human PENK

Isotype: IgG

Information d'application

Indications d'application: WB: 1:100-1000, IHC-P: 1:100-500, IF(IHC-P): 1:50-200
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur Enkephalin

Antigène: Enkephalin (PENK) (Proenkephalin (PENK))

Autre désignation: Enkephalin

Sujet:

Synonyms: Enkephalin A, PENK, P ENK, Preproencephalin A, Proenkephalin A, Proenkephalin, Synenkephalin, Opioid growth factor, OGF, Leu enkephalin, Met enkephalin, PENK protein, ProenkephalinA, lipotropin gamma, COLI_HUMAN.

Background: This gene encodes a polypeptide hormone precursor that undergoes extensive, tissue-specific, post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases. There are eight potential cleavage sites within the polypeptide precursor and, depending on tissue type and the available convertases, processing may yield as many as ten biologically active peptides involved in diverse cellular functions. The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used, adrenocorticotrophin, essential for normal steroidogenesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products. In other tissues, including the hypothalamus, placenta, and epithelium, all cleavage sites may be used, giving rise to peptides with roles in pain and energy homeostasis, melanocyte stimulation, and immune modulation. These include several distinct melanotropins, lipotropins, and endorphins that are contained within the adrenocorticotrophin and beta-lipotropin peptides. Mutations in this gene have been associated with early onset obesity, adrenal insufficiency, and red hair pigmentation. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008].

ID gène: 5179

Pathways: Stem Cell Maintenance