TDRD1 anticorps (AA 201-300)

N° du produit ABIN678443

L’anticorps Lapin Polyclonal anti-TDRD1 a été validé pour ELISA, IHC (p), IF (cc), IF (p) et IHC (fro). Il convient pour détecter TDRD1 dans des échantillons de Souris.

Aperçu rapide pour TDRD1 anticorps (AA 201-300) (ABIN678443)

Antigène: TDRD1 (Tudor Domain Containing 1 (TDRD1))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TDRD1 est non-conjugé

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-TDRD1 anticorps

Épitope: AA 201-300

Réactivité croisée: Souris

Homologie: Human,Rat,Dog,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human TDRD1

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur TDRD1

Antigène: TDRD1 (Tudor Domain Containing 1 (TDRD1))

Autre désignation: TDRD1

Sujet:

Synonyms: CT41.1, Tudor domain-containing protein 1, Cancer/testis antigen 41.1, TDRD1

Background: Plays a central role during spermatogenesis by participating in the repression transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Required for the localization of Piwi proteins to the meiotic nuage. Involved in the piRNA metabolic process by ensuring the entry of correct transcripts into the normal piRNA pool and limiting the entry of cellular transcripts into the piRNA pathway. May act by allowing the recruitment of piRNA biogenesis or loading factors that ensure the correct entry of transcripts and piRNAs into Piwi proteins (By similarity).

ID gène: 56165

UniProt: Q9BXT4

Pathways: Ribonucleoprotein Complex Subunit Organization