LAMP2 anticorps
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- Antigène Voir toutes LAMP2 Anticorps
- LAMP2 (Lysosomal-Associated Membrane Protein 2 (LAMP2))
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Reactivité
- Humain, Chien, Vison
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp LAMP2 est non-conjugé
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Application
- Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunofluorescence (IF)
- Specificité
- Recognizes canine CD107b, otherwise known as LAMP-2, a 95kD heavily-glycosylated type I integral lysosomal glycoprotein, shown to share high N-terminal amino acid sequence homology with human, mouse and rat CD107b. Lysosomes are membrane-bound organelles found within the cytoplasm of most cells, which contain hydrolytic enzymes and act as the major compartment for heterophagic and autophagic digestion. Members of the lysosomal-associated membrane protein family (LAMPS) are believed to play an important role in protecting the lysosomal membrane from protease degradation and are involved in lectin-mediated cell adhesion. Evidence shows that CD107b is involved in the lysosomal uptake of cytosolic proteins and the endocytic pathway and human studies have revealed a correlation between the level of surface expression of CD107b on tumor cells and their metastatic potential. Clone AC17 has been shown as suitable for use in Electron Microscopy.
- Aucune reactivité croisée
- Souris, Rat (Rattus)
- Purification
- Protein G purified
- Immunogène
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MDCK (Madin-Darby Canine Kidney) cells.
Type of Immunogen: Cells - Clone
- AC17
- Isotype
- IgG1
- Top Product
- Discover our top product LAMP2 Anticorps primaire
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- Indications d'application
- Approved: Flo, IF, IP, WB (1:100 - 1:500)
- Commentaires
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Target Species of Antibody: Dog
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- PBS, 0.09 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- 4°C or -20°C, Avoid freeze-thaw cycles.
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- Antigène
- LAMP2 (Lysosomal-Associated Membrane Protein 2 (LAMP2))
- Autre désignation
- LAMP2 / CD107b (LAMP2 Produits)
- Synonymes
- anticorps CD107b, anticorps LAMP-2, anticorps LAMPB, anticorps LGP110, anticorps Lamp-2, anticorps Lamp-2a, anticorps Lamp-2b, anticorps Lamp-2c, anticorps Mac3, anticorps cd107b, anticorps lamp-2, anticorps lampb, anticorps LAMP2, anticorps lamp2, anticorps DKFZp459J126, anticorps LGP-B, anticorps sb:cb587, anticorps wu:fb14a06, anticorps zgc:103532, anticorps lysosomal associated membrane protein 2, anticorps lysosomal-associated membrane protein 2, anticorps lysosomal-associated membrane protein 2 S homeolog, anticorps lysosomal membrane glycoprotein 2, anticorps LAMP2, anticorps Lamp2, anticorps lamp2.S, anticorps lamp2
- Sujet
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Name/Gene ID: LAMP2
Family: Cancer
Synonyms: LAMP2, CD107b, CD107b antigen, LAMPB, LGP110, LAMP-2 - ID gène
- 3920
- Pathways
- Autophagy
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