PKA/C alpha/beta (AA 251-351) anticorps

N° du produit ABIN680093

L’anticorps Lapin Polyclonal anti- a été validé pour WB, ELISA et IHC (p). Il convient pour détecter dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour PKA/C alpha/beta (AA 251-351) anticorps (ABIN680093)

Antigène: PKA/C alpha/beta

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit

Épitope: AA 251-351

Réactivité croisée: Humain, Souris, Rat

Homologie: Dog,Cow,Pig,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human PKA beta

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: PKA/C alpha/beta

Autre désignation: PKA C alpha+beta

Sujet:

Synonyms: PKA C beta, PKACB, PRKACB, Protein kinase cAMP dependent catalytic beta.

Background: cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP dependent protein kinase (AMPK), which transduces the signal through phosphorylation of different target proteins. The inactive holoenzyme of AMPK is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits of AMPK have been identified in humans. PKA beta (catalytic subunit) is a member of the Ser/Thr protein kinase family and is a catalytic subunit of AMPK.

ID gène: 81491