PRKACA/PRKACB anticorps (AA 251-351) (Biotin)

N° du produit ABIN680095

Cet anticorps Lapin Polyclonal détecte spécifiquement PRKACA/PRKACB dans WB, IHC (p) et IHC (fro). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour PRKACA/PRKACB anticorps (AA 251-351) (Biotin) (ABIN680095)

Antigène: PRKACA/PRKACB (PRKACA/B) (Protein Kinase A, alpha/beta (PRKACA/B))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRKACA/PRKACB est conjugé à/à la Biotin

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-PRKACA/PRKACB anticorps (Biotin)

Épitope: AA 251-351

Fonction: PKA C alpha + beta Polyclonal Antibody, Biotin Conjugated

Réactivité croisée: Humain, Souris, Rat

Homologie: Dog,Cow,Pig,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human PKA beta

Isotype: IgG

Information d'application

Indications d'application: WB(1:300-5000), IHC-P(1:200-400), IHC-F(1:100-500)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur PRKACA/PRKACB

Antigène: PRKACA/PRKACB (PRKACA/B) (Protein Kinase A, alpha/beta (PRKACA/B))

Autre désignation: PKA C alpha+beta

Sujet:

Synonyms: PKA C beta, PKACB, PRKACB, Protein kinase cAMP dependent catalytic beta.

Background: cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP dependent protein kinase (AMPK), which transduces the signal through phosphorylation of different target proteins. The inactive holoenzyme of AMPK is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits of AMPK have been identified in humans. PKA beta (catalytic subunit) is a member of the Ser/Thr protein kinase family and is a catalytic subunit of AMPK.

ID gène: 81491